Evidence map›Paper›PMID 41595998›Full record

ArticleBioengineering (Basel, Switzerland)2026

Polyethylene Stresses in Lumbar Total Joint Replacement Under Elevated Loading: Insights from an Anatomic Finite Element Model.

Steven A Rundell, Hannah Spece, Ronald V Yarbrough, Steven M Kurtz

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Steven A RundellExplico Inc., Novi, MI 48375, USA.
Hannah SpeceSchool of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, USA.
Ronald V Yarbrough3Spine Inc., Chattanooga, TN 37402, USA.
Steven M KurtzSchool of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA 19104, USA.ORCID 0000-0002-3885-500X

Funding

3Spine n/a
6 · The paper itself

Abstract

The goal of this study was to assess elevated spinal loading conditions and their effect on the polyethylene stresses of a lumbar total joint replacement (L-TJR). A previously validated lumbar spine finite element model was virtually implanted with an L-TJR at L4-L5 and exposed to three elevated loading conditions: (1) 95th-percentile male body weight while bending forward, (2) combined ±7.5 Nm axial torsion and lateral bending, and (3) ASTM F2423 aggressive loading (1850 N plus 10-12 Nm bending). Combined torsion and lateral bending were considered because these loads and moments may be coupled in demanding real-world scenarios. Across all conditions, contact at the bearing remained confined to the intended spherical surfaces, consistent with Mode I in vitro wear tests, with no evidence of impingement. Contact stresses and von Mises stresses were considered acceptable based on the simulated results of Mode IV impingement tests. Only in one scenario-95th-percentile male body weight with multiaxial torsion-did von Mises stress in the polyethylene slightly exceed the stresses associated with impingement (<5%). These findings are useful in establishing the upper biomechanical loading limits for the L-TJR design beyond the 50th-percentile loading levels employed by standard in vitro tests. Future validation efforts such as a comparison with retrieval analyses or clinical data will further strengthen the model's applicability to current and future questions of interest and contexts of use. Additional work may expand the modeling framework to incorporate patient-specific anatomy, variable implant positioning conditions, and a broader range of physiological load scenarios.

Indexed as

arthroplastycontact pressureelevated loadingfinite element modelhighly crosslinked polyethylenespinevon Mises stresswear

Identifiers

PMID41595998
PMCPMC12838315

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.