ArticleBioengineering (Basel, Switzerland)2025
Integrated Analysis of an Innovative Composite Polycaprolactone Membrane and a Jason Membrane in Guided Bone Regeneration.
Article in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
In the context of guided bone regeneration (GBR), the selection of an appropriate resorbable membrane plays a crucial role in the clinical success of the procedure. Precise knowledge about the distinct differences in properties is fundamental for correct selection of the membrane. This article presents an integrated comparative analysis between membranes, conducted for this given purpose and one step beyond: to fabricate a novel membrane with dedicated enhanced properties according to the targeted function. Our previous analysis showed that polymer membranes that met most histopathological criteria also produced the most remarkable results when radiologically observed. The most effective scaffolds were those containing active macromolecules released conditionally and staged. The PLGA and polycaprolactone scaffolds were found in this category and they granted a marked increase in bone density and improvement in osteoinduction. Based on these results, we decided to create a new polycaprolactone membrane in order to compare it with a standard currently on the market, the Jason membrane. The Jason
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