Evidence map›Paper›PMID 41595862›Full record

ArticleInternational journal of environmental research and public health2026

Impact of Social Determinants of Health on the Incidence of Tuberculosis in Central Asia.

Assiya Kussainova, Laura Kassym, Almas Kussainov, Ainash Orazalina, Yerbol Smail, Gulmira Derbissalina, Zhanagul Bekbergenova, Ulzhan Kozhakhmetova, Elvira Aitenova, Yuliya Semenova

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Long-Term Epidemiological Trends and Regional Disparities in Male Infertility in Central Asia (1991-2023).International journal of environmental research and public health · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Assiya KussainovaDepartment of General Medical Practice with a Course of Evidence-Based Medicine, Astana Medical University, Astana 010000, Kazakhstan.
Laura KassymDepartment of General Medical Practice with a Course of Evidence-Based Medicine, Astana Medical University, Astana 010000, Kazakhstan.
Almas KussainovDepartment of Psychiatry and Narcology, NJSC Astana Medical University, Astana 010000, Kazakhstan.
Ainash OrazalinaDepartment of Molecular Biology and Medical Genetics Named After the Academician of National Academy of Sciences Republic of Kazakhstan Raissov T. K., NJSC Semey Medical University, Semey 071400, Kazakhstan.ORCID 0000-0003-4594-0138
Yerbol SmailDepartment of Infectious Diseases, Dermatovenereology and Immunology, NJSC Semey Medical University, Semey 071400, Kazakhstan.
Gulmira DerbissalinaDepartment of General Medical Practice with a Course of Evidence-Based Medicine, Astana Medical University, Astana 010000, Kazakhstan.
Zhanagul BekbergenovaDepartment of General Medical Practice with a Course of Evidence-Based Medicine, Astana Medical University, Astana 010000, Kazakhstan.ORCID 0000-0002-6146-3784
Ulzhan KozhakhmetovaDepartment of General Medical Practice with a Course of Evidence-Based Medicine, Astana Medical University, Astana 010000, Kazakhstan.
Elvira AitenovaDepartment of General Medical Practice with a Course of Evidence-Based Medicine, Astana Medical University, Astana 010000, Kazakhstan.ORCID 0009-0007-9006-8795
Yuliya SemenovaSchool of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.ORCID 0000-0003-1324-7806

Funding

Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan AP25794711
6 · The paper itself

Abstract

BACKGROUND/

objectivesTuberculosis (TB) remains a major global health challenge influenced by social determinants of health (SDHs) such as poverty, overcrowding, malnutrition, and limited healthcare access. Although Central Asia (CA) has achieved progress through vaccination, screening, and treatment, the region continues to face severe disease consequences, unstable incidence patterns, and an escalating challenge of TB resistant to first-line drugs. This study aimed to analyze TB incidence dynamics in Kazakhstan, Tajikistan, the Kyrgyz Republic, Turkmenistan, and Uzbekistan from 2000-2023, forecast trends to 2030, and identify key SDHs shaping the epidemic.

methodsData on TB incidence were obtained from the World Bank DataBank for 2000-2023. Of 61 socioeconomic, environmental, and health-related indicators, 29 were included in the analysis. Statistical procedures in SPSS (v24.0) involved time-series forecasting through 2030, calculation of average annual percentage change (AAPC), correlation testing, and linear regression, with significance set at

resultsTB incidence generally declined across CA during 2000-2023, though trends varied by country. Forecasts suggest continued decreases in Turkmenistan and Uzbekistan, while Kazakhstan, Tajikistan, and the Kyrgyz Republic display fluctuating or nonsignificant patterns, likely influenced by SDHs. Regression analyses indicated that anemia, undernourishment, and population density showed a positive relationship with TB incidence, while clean fuel access, physician density, and Gross Domestic Product per capita (GDP) were inversely related.

conclusionsThe findings highlight the heterogeneous nature of TB dynamics in CA and the possible role of SDHs. Enhanced surveillance, nutritional and social interventions are required to sustain progress toward End TB targets.

Indexed as

Social Determinants of HealthTuberculosisAsia, CentralHumansIncidenceCentral AsiaincidenceKazakhstansocial determinants of healthtuberculosis

Identifiers

PMID41595862
PMCPMC12840887

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.