Evidence map›Paper›PMID 41595689›Full record

ArticleBiomedicines2026

Surfactin Inhibits Osteoclast Differentiation by Negatively Regulating the Elk1-AP-1-NFATc1 Axis.

Kazuki Maruyama, Ayaka Koga, Yuki Kodama, Ryota Yamasaki, Yoshie Nagai-Yoshioka, Jun J Miyamoto, Kayoko Kuroishi, Kaori Gunjigake, Tatsuo Kawamoto, Wataru Ariyoshi

Abstract read
In one paragraph

Article in Biomedicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kazuki MaruyamaDivision of Orofacial Functions and Orthodontics, Department of Craniofacial Growth and Development, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan.
Ayaka KogaDivision of Infections and Molecular Biology, Department of Advanced Pathophysiological Science, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan.ORCID 0009-0008-6259-6432
Yuki KodamaDivision of Infections and Molecular Biology, Department of Advanced Pathophysiological Science, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan.
Ryota YamasakiDivision of Infections and Molecular Biology, Department of Advanced Pathophysiological Science, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan.ORCID 0000-0003-1152-3248
Yoshie Nagai-YoshiokaDivision of Infections and Molecular Biology, Department of Advanced Pathophysiological Science, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan.ORCID 0009-0004-2615-6545
Jun J MiyamotoDivision of Orofacial Functions and Orthodontics, Department of Craniofacial Growth and Development, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan.
Kayoko KuroishiDivision of Orofacial Functions and Orthodontics, Department of Craniofacial Growth and Development, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan.
Kaori GunjigakeDivision of Orofacial Functions and Orthodontics, Department of Craniofacial Growth and Development, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan.ORCID 0000-0003-3642-289X
Tatsuo KawamotoDivision of Orofacial Functions and Orthodontics, Department of Craniofacial Growth and Development, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan.ORCID 0000-0002-3098-5440
Wataru AriyoshiDivision of Infections and Molecular Biology, Department of Advanced Pathophysiological Science, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan.ORCID 0000-0002-6533-5683

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AP-1Elk1NFATc1osteoclastsurfactin

Identifiers

PMID41595689
PMCPMC12838702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.