Evidence map›Paper›PMID 41595596›Full record

ArticleBiomedicines2025

The TRPV1 Channel Modulator Imidazo[1,2-a]Indole Derivative Exhibits Pronounced and Versatile Anti-Inflammatory Activity In Vivo.

Pavel A Galenko-Yaroshevsky, Anait V Zelenskaya, Konstantin F Suzdalev, Tatyana N Popova, Aleksandra N Kvetkina, Margarita M Shamatova, Elena N Chuyan, Marina Yu Ravaeva, Roman A Murashko, Tereza R Glechyan and 9 more

Abstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Pavel A Galenko-YaroshevskyDepartment of Pharmacology, Kuban State Medical University, Krasnodar 350063, Russia.ORCID 0000-0003-3190-1437
Anait V ZelenskayaDepartment of Pharmacology, Kuban State Medical University, Krasnodar 350063, Russia.ORCID 0000-0001-9512-2526
Konstantin F SuzdalevFaculty of Chemistry, Southern Federal University, Rostov-on-Don 344090, Russia.ORCID 0000-0003-4879-0577
Tatyana N PopovaDepartment of Medical Biochemistry, Molecular and Cell Biology, Voronezh State University, Voronezh 394018, Russia.ORCID 0000-0002-9660-3054
Aleksandra N KvetkinaLaboratory of Molecular Pharmacology and Biomedicine, Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Vladivostok 690022, Russia.ORCID 0000-0002-0937-002X
Margarita M ShamatovaLaboratory of Neuroreceptors and Neuromodulators, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 119997, Russia.ORCID 0009-0007-1511-1538
Elena N ChuyanInstitute of Biochemical Technologies, Ecology, and Pharmacy, V.I. Vernadsky Crimean Federal University, Simferopol 295001, Russia.
Marina Yu RavaevaInstitute of Biochemical Technologies, Ecology, and Pharmacy, V.I. Vernadsky Crimean Federal University, Simferopol 295001, Russia.ORCID 0000-0002-6081-1628
Roman A MurashkoDepartment of Public Health and Healthcare, Kuban State Medical University, Krasnodar 350063, Russia.ORCID 0000-0001-8873-8461
Tereza R GlechyanDepartment of Pharmacology, Kuban State Medical University, Krasnodar 350063, Russia.
Alina V SergeevaDepartment of Pharmacology, Kuban State Medical University, Krasnodar 350063, Russia.ORCID 0000-0003-4335-2156
Narek N IshkhanyanDepartment of Pharmacology, Kuban State Medical University, Krasnodar 350063, Russia.
Olga N GulevskayaDepartment of Adaptive Physical Education, Kuban State University of Physical Education, Sports, and Tourism, Krasnodar 350015, Russia.ORCID 0000-0001-7205-2473
Vladislav I Chubinskiy-NadezhdinGroup of Ionic Mechanisms of Cell Signaling, Department of Intracellular Signaling and Transport, Institute of Cytology, Russian Academy of Sciences, St. Petersburg 194064, Russia.ORCID 0000-0002-8488-6130
Evgenii D Kryl'skiiDepartment of Medical Biochemistry, Molecular and Cell Biology, Voronezh State University, Voronezh 394018, Russia.ORCID 0000-0002-8855-5515
Nadezhda A PriymenkoLaboratory of Molecular Pharmacology and Biomedicine, Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Vladivostok 690022, Russia.
Anna A KlimovichLaboratory of Molecular Pharmacology and Biomedicine, Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Vladivostok 690022, Russia.
Elena V LeychenkoLaboratory of Molecular Pharmacology and Biomedicine, Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Vladivostok 690022, Russia.ORCID 0000-0002-2360-1365
Sergey A KozlovLaboratory of Neuroreceptors and Neuromodulators, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 119997, Russia.ORCID 0000-0002-0242-4240

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

animal modelsanti-inflammatory actioncytokinesimidazo[1,2-a]indole derivativeNSAIDsTRPV1 inhibitor

Identifiers

PMID41595596
PMCPMC12839412

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.