Evidence map›Paper›PMID 41595578›Full record

ArticleBiomedicines2025

Integrated Biomarker-Volumetric Profiling Defines Neurodegenerative Subtypes and Predicts Neuroaxonal Injury in Multiple Sclerosis Based on Bayesian and Machine Learning Analyses.

Alin Ciubotaru, Roxana Covali, Cristina Grosu, Daniel Alexa, Laura Riscanu, Bîlcu Robert-Valentin, Radu Popa, Gabriela Dumachita Sargu, Cristina Popa, Cristiana Filip and 4 more

Abstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Observational
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alin CiubotaruGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0009-0003-2079-2383
Roxana CovaliDepartment of Radiology, Biomedical Engineering Faculty, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0002-7386-0859
Cristina GrosuGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Daniel AlexaGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Laura RiscanuDepartment of Morphofunctional Sciences, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Bîlcu Robert-ValentinDoctoral School, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Radu PopaDepartment of Vascular Surgery, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Gabriela Dumachita SarguDepartment of Obstetrics and Gynecology, Elena Doamna Obstetrics and Gynecology University Hospital, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Cristina PopaFaculty of Dental Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Cristiana FilipDepartment of Biochemistry, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Laura-Elena CucuDoctoral School, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0009-0000-1544-1325
Albert VamanuBasic and Clinical Neuroscience Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 8AF, UK.
Victor ConstantinescuGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Emilian Bogdan IgnatGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0002-6952-9741

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bayesian analysisbrain volumetryendophenotypesmachine learningmultiple sclerosisneurodegenerationpredictive modellingserum neurofilament light chain

Identifiers

PMID41595578
PMCPMC12837661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.