Evidence map›Paper›PMID 41595332›Full record

ReviewHealthcare (Basel, Switzerland)2026

Mindfulness Components and Their Clinical Efficacy: A Critical Review of an Ongoing Debate.

Andrea Lizama-Lefno, Krystel Mojica, Mayte Serrat, Carla Olivari, Ángel Roco-Videla, Sergio V Flores

Abstract readReview
In one paragraph

Review in Healthcare (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrea Lizama-LefnoDepartment of Development and Postgraduate, Universidad Autónoma de Chile, Santiago 8420524, Chile.ORCID 0000-0001-8764-6928
Krystel MojicaFundación Núcleo de Investigación DOLMEN, Santiago 7580023, Chile.ORCID 0009-0004-7730-0615
Mayte SerratVall d'Hebron Barcelona Hospital Campus, Vall d'Hebron Hospital Universitari, 08035 Barcelona, Spain.ORCID 0000-0002-5591-9407
Carla OlivariEscuela de Salud Pública, Universidad de Chile, Santiago 8380000, Chile.ORCID 0000-0002-0461-0856
Ángel Roco-VidelaFacultad de Ingeniería, Universidad Católica de la Santísima Concepción, Concepción 4090541, Chile.ORCID 0000-0001-8850-1018
Sergio V FloresCentro de Investigación en Medicina de Altura, Universidad Arturo Prat, Iquique 1110939, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid expansion of mindfulness research has generated both enthusiasm and controversy regarding its actual clinical value. While meditation is often regarded as the central mechanism of mindfulness-based interventions, other components such as psychoeducation and informal practice may play an equally significant role in improving mental health outcomes. This critical review examines the relative contributions of these elements to the therapeutic impact of mindfulness and clarifies the extent to which its effects are comparable to established treatments, particularly Cognitive Behavioral Therapy (CBT). Evidence from meta-analyses and high-quality trials indicates that mindfulness programs achieve moderate efficacy in reducing symptoms of anxiety, depression, and stress, but effect sizes are frequently inflated by methodological limitations. Importantly, cognitive and emotional regulation skills, especially acceptance and non-judgment, appear to sustain long-term benefits more consistently than meditation alone. These findings highlight the need for rigorous longitudinal studies and component-focused designs to identify the mechanisms that drive clinical change. By distinguishing between evidence-based applications and overstated claims, this review contributes to a more balanced understanding of mindfulness and its appropriate integration into healthcare.

Indexed as

clinical efficacycognitive behavioral therapyhealth educationmeditationmental healthmindfulness

Identifiers

PMID41595332
PMCPMC12840811

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.