Evidence map›Paper›PMID 41594938›Full record

ReviewBiology2026

Durable Management of Plant Viruses: Insights into Host Resistance and Tolerance Mechanisms.

Muhammad Zeshan Ahmed, Chenchen Zhao, Calum Wilson, Meixue Zhou

Abstract readReview
In one paragraph

Review in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Muhammad Zeshan AhmedTasmanian Institute of Agriculture, University of Tasmania, Launceston 7250, Australia.
Chenchen ZhaoTasmanian Institute of Agriculture, University of Tasmania, Launceston 7250, Australia.ORCID 0000-0001-8586-6206
Calum WilsonTasmanian Institute of Agriculture, University of Tasmania, Launceston 7250, Australia.ORCID 0000-0001-5434-3816
Meixue ZhouTasmanian Institute of Agriculture, University of Tasmania, Launceston 7250, Australia.ORCID 0000-0003-3009-7854

Funding

Grains Research and Development Corporation UOQ2405-015RTX
6 · The paper itself

Abstract

Plant viruses cause substantial yield and quality losses worldwide, and their rapid evolution can erode deployed host resistance. This review synthesizes current knowledge of antiviral resistance and tolerance mechanisms, using barley yellow dwarf virus (BYDV) in cereals as an illustrative case study. We first summarize key layers of plant antiviral immunity, including pre-formed physical and chemical barriers, dominant and recessive resistance genes, RNA silencing, hormone-regulated defense signaling, and degradation pathways such as the ubiquitin-proteasome system and selective autophagy. We then discuss how these mechanisms are exploited in breeding and biotechnology, covering conventional introgression, marker-assisted selection, QTL mapping and pyramiding, induced variation (mutation breeding and TILLING/ecoTILLING), transgenic strategies (pathogen-derived resistance and plantibodies), RNA interference-based approaches, and CRISPR-enabled editing of susceptibility factors. Finally, we highlight emerging nano-enabled tools and propose integrated strategies that combine genetic resistance with surveillance and vector management to improve durability under climate change and ongoing viral diversification.

Indexed as

breeding for virus resistanceplant defense signaling pathwaysplant–virus interactionsresistance (R) genesRNA interference (RNAi)zig-zag model

Identifiers

PMID41594938
PMCPMC12837541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.