Evidence map›Paper›PMID 41594851›Full record

ArticleBiology2026

Evaluating the Immunogenicity of a Recombinant

Rongxing Fan, Yuanqi Bi, Shanshan Yang, Shaopeng Yao, Wen An, Zhongtian Wang, Zengjun Ma, Ping Rui, Tao Song, Lili Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rongxing FanCollege of Animal Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao 066000, China.
Yuanqi BiCollege of Animal Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao 066000, China.
Shanshan YangCollege of Animal Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao 066000, China.
Shaopeng YaoCollege of Animal Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao 066000, China.
Wen AnCollege of Animal Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao 066000, China.
Zhongtian WangCollege of Animal Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao 066000, China.
Zengjun MaCollege of Animal Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao 066000, China.ORCID 0000-0003-4379-7534
Ping RuiCollege of Animal Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao 066000, China.
Tao SongCollege of Animal Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao 066000, China.ORCID 0000-0002-9730-7855
Lili WangCollege of Animal Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao 066000, China.
Fengsai LiCollege of Animal Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao 066000, China.

Funding

the Fundamental Research Funds for the Provincial Universities 2025JK008the Science and Technology Research Project of colleges and universities in Hebei province BJK2023012the Scientific Research Fund of the Hebei Normal Unixersity of Science and Technology 2023YB004
6 · The paper itself

Abstract

Transmissible gastroenteritis (TGE), caused by the TGE virus (TGEV), is a highly contagious enteric disease characterized by vomiting, dehydration, and watery diarrhea. It mainly endangers piglets within two weeks of age, with a 100% mortality rate, inflicting severe economic losses on the global swine industry. Since enteric tropism of the virus and mucosa serves as the first line of defense against viral invasion, an oral vaccine inducing sufficient secretory immunoglobulin A (SIgA) antibodies in animals should be developed. Being a generally recognized as safe (GRAS) microorganism,

Indexed as

AD antigenic epitopeBacillus subtilisimmunogenicitythe B subunit of the heat-labile enterotoxintransmissible gastroenteritis

Identifiers

PMID41594851
PMCPMC12838399

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.