Evidence map›Paper›PMID 41594700›Full record

ReviewBiomolecules2026

Mechanisms of Metabolic Reprogramming Regulating Immunosuppression in the Gastric Cancer Tumor Microenvironment.

Wenting Dong, Xuepeng Qian, Honglin Liu, Jinhai Huo, Weiming Wang

Abstract readReview
In one paragraph

Review in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wenting DongInstitute of Chinese Materia Medica, Heilongjiang Academy of Chinese Medicine Science, Harbin 150036, China.ORCID 0000-0003-0866-0962
Xuepeng QianInstitute of Chinese Materia Medica, Heilongjiang Academy of Chinese Medicine Science, Harbin 150036, China.ORCID 0009-0007-6956-5957
Honglin LiuInstitute of Chinese Materia Medica, Heilongjiang Academy of Chinese Medicine Science, Harbin 150036, China.ORCID 0009-0004-1567-4195
Jinhai HuoInstitute of Chinese Materia Medica, Heilongjiang Academy of Chinese Medicine Science, Harbin 150036, China.ORCID 0000-0002-9714-4312
Weiming WangInstitute of Chinese Materia Medica, Heilongjiang Academy of Chinese Medicine Science, Harbin 150036, China.ORCID 0009-0007-6482-426X

Funding

the Key Science and Technology Program of Heilongjiang Province, China 2022ZXJ02C01
6 · The paper itself

Abstract

Immunotherapy, especially immune checkpoint inhibitors (ICIs), has become one of the core therapeutic approaches in cancer in recent years. It demonstrates remarkable efficacy in the treatment of melanoma and lung cancer. Conversely, its use in treating gastric cancer (GC) is not associated with considerable benefits. The high heterogeneity of GC and the tumor microenvironment (TME) may directly influence this phenomenon. This review focuses on the correlation between

Indexed as

Stomach NeoplasmsTumor MicroenvironmentAnimalsHelicobacter InfectionsHelicobacter pyloriHumansImmunosuppression TherapyImmunotherapyMetabolic Reprogramminggastric cancerHelicobacter pyloriimmune microenvironmentmetabolic reprogrammingmolecular subtypestherapeutic strategies

Identifiers

PMID41594700
PMCPMC12838900

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.