Evidence map›Paper›PMID 41594685›Full record

ArticleBiomolecules2026

Novel Dorsomorphin Derivatives: Molecular Modeling, Synthesis, and Bioactivity Evaluation.

Evangelia N Tzanetou, Sandra Liekens, Konstantinos M Kasiotis, Nikolas Fokialakis, Nikolaos Tsafantakis, Raul SanMartin, Haralampos Tzoupis, Konstantinos D Papavasileiou, Antreas Afantitis, Serkos A Haroutounian

Abstract read
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Evangelia N TzanetouLaboratory of Nutritional Physiology and Feeding, Department of Animal Sciences and Aquaculture, Agricultural University of Athens, Iera Odos 75, 11855 Athens, Greece.ORCID 0000-0001-9568-2283
Sandra LiekensRega Institute for Medical Research, KU Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium.
Konstantinos M KasiotisLaboratory of Nutritional Physiology and Feeding, Department of Animal Sciences and Aquaculture, Agricultural University of Athens, Iera Odos 75, 11855 Athens, Greece.ORCID 0000-0001-6631-0667
Nikolas FokialakisDepartment of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, University of Athens, Panepistimiopolis, Zografou, 15771 Athens, Greece.ORCID 0000-0001-7028-1870
Nikolaos TsafantakisDepartment of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, University of Athens, Panepistimiopolis, Zografou, 15771 Athens, Greece.ORCID 0000-0002-6829-9673
Raul SanMartinDepartment of Organic and Inorganic Chemistry, Faculty of Science and Technology, University of the Basque Country, (UPV-EHU), 48940 Leioa, Spain.ORCID 0000-0002-8105-1947
Haralampos TzoupisDepartment of ChemoInformatics, NovaMechanics Ltd., Nicosia 1070, Cyprus.ORCID 0000-0002-1534-2762
Konstantinos D PapavasileiouDepartment of ChemoInformatics, NovaMechanics Ltd., Nicosia 1070, Cyprus.
Antreas AfantitisDepartment of ChemoInformatics, NovaMechanics Ltd., Nicosia 1070, Cyprus.ORCID 0000-0002-0977-8180
Serkos A HaroutounianLaboratory of Nutritional Physiology and Feeding, Department of Animal Sciences and Aquaculture, Agricultural University of Athens, Iera Odos 75, 11855 Athens, Greece.ORCID 0000-0002-5841-3460

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dorsomorphin, a pyrazolo[1,5-

Indexed as

Antineoplastic AgentsProtein Kinase InhibitorsPyrazolesPyrimidinesAnimalsCattleCell Line, TumorCell ProliferationEndothelial CellsHeLa CellsHumansMiceModels, MolecularMolecular Docking SimulationAntineoplastic AgentsdorsomorphinProtein Kinase InhibitorsPyrazolesPyrimidinesantiproliferativedorsomorphinmicrowave-assisted synthesismolecular modelingpyrazolo[1,5-a]pyrimidine

Identifiers

PMID41594685
PMCPMC12839441

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.