Evidence map›Paper›PMID 41594677›Full record

ArticleBiomolecules2026

Magnetic Nanocarriers with ICPTES- and GPTMS-Functionalized Quaternary Chitosan for pH-Responsive Doxorubicin Release.

Sofia F Soares, Ana L M Machado, Beatriz S Cardoso, Diogo Marinheiro, Nelson Andrade, Fátima Martel, Ana L Daniel-da-Silva

Abstract read
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sofia F SoaresCICECO-Aveiro Institute of Materials, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-3172-5437
Ana L M MachadoCICECO-Aveiro Institute of Materials, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.
Beatriz S CardosoCICECO-Aveiro Institute of Materials, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.
Diogo MarinheiroCICECO-Aveiro Institute of Materials, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-1265-5744
Nelson AndradeUnit of Biochemistry, Department of Biomedicine, Faculty of Medicine of Porto, University of Porto, 4200-319 Porto, Portugal.ORCID 0000-0003-2600-8599
Fátima MartelUnit of Biochemistry, Department of Biomedicine, Faculty of Medicine of Porto, University of Porto, 4200-319 Porto, Portugal.ORCID 0000-0002-0525-3416
Ana L Daniel-da-SilvaCICECO-Aveiro Institute of Materials, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0001-6581-8880

Funding

Fundação para a Ciência e Tecnologia 10.54499/2021.05673.BDFundação para a Ciência e Tecnologia 2023.06221.CEECIND/CP2840/CT0019Fundação para a Ciência e Tecnologia CEECIND/03075/2018/CP1559/CT0020; DOI: 10.54499/CEECIND/03075/2018/CP1559/CT0020Fundação para a Ciência e Tecnologia UID/50011/2025 (DOI 10.54499/UID/50011/2025) & LA/P/0006/2020 (DOI 10.54499/LA/P/0006/2020)
6 · The paper itself

Abstract

Smart nanocarriers are being increasingly explored to improve the performance selectivity of cancer chemotherapy. Here, two pH-responsive magnetic nanocarriers were developed using quaternary chitosan (HTCC) functionalized with 3-(triethoxysilyl)propyl isocyanate- ICPTES (MNP-HTCC1) or 3-(glycidyloxypropyl)trimethoxysilane-GPTMS (MNP-HTCC2) to form hybrid silica shells on Fe

Indexed as

ChitosanDoxorubicinDrug CarriersMagnetite NanoparticlesAntibiotics, AntineoplasticDrug LiberationHumansHydrogen-Ion ConcentrationIsocyanatesMCF-7 CellsSilanesAntibiotics, AntineoplasticChitosanDoxorubicinDrug CarriersIsocyanatesMagnetite NanoparticlesSilanesdoxorubicin releasemagnetic nanocarrierspH-responsive drug deliveryquaternary chitosansurface functionalization

Identifiers

PMID41594677
PMCPMC12839120

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.