ReviewBiomolecules2026
Ionotropic Receptors as Potential Targets Against Insect-Transmitted Diseases.
Review in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 author.
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Abstract
Insects can remotely detect human temperature, odor, and other stimuli as part of their host-seeking strategy. Such detection involves specific biomolecules, whose inhibition could limit host spotting and decrease the spread of insect-transmitted diseases. In this framework, invertebrate-specific ionotropic receptors (IRs) provide a potential molecular target to disable the insect's capability to detect stimuli from prospective hosts. While several IRs have been studied in disease-transmitting insects, their inhibition remains unexplored. The rational design and development of such inhibitors requires the detailed characterization of the structure and functional mechanisms of IRs. Here, I discuss a possible, exploratory, and long-term approach for IR inhibition, which is based on research in mammalian thermosensitive transient receptor potential ion channels.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.