Microcystin-LR-Induced Oxidative Stress, Transcriptome Changes, Intestinal Microbiota, and Histopathology in

You Wang, Bingjie Wang, Zhuolin He, Jiaxin Chen, Chenyang Liu, Zhanqi Wang, Muhammad Irfan, Lixia Zhang

Abstract read

In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

You WangDepartment of Ecology, College of Life Sciences, Henan Normal University, Xinxiang 453007, China.

Bingjie WangDepartment of Ecology, College of Life Sciences, Henan Normal University, Xinxiang 453007, China.

Zhuolin HeDepartment of Ecology, College of Life Sciences, Henan Normal University, Xinxiang 453007, China.

Jiaxin ChenDepartment of Ecology, College of Life Sciences, Henan Normal University, Xinxiang 453007, China.

Chenyang LiuDepartment of Ecology, College of Life Sciences, Henan Normal University, Xinxiang 453007, China.

Zhanqi WangKey Laboratory of Vector Biology and Pathogen Control of Zhejiang Province, College of Life Sciences, Huzhou University, Huzhou 313000, China.ORCID 0000-0002-7953-6128

Muhammad IrfanDepartment of Biotechnology, University of Sargodha, Sargodha 40100, Pakistan.

Lixia ZhangDepartment of Ecology, College of Life Sciences, Henan Normal University, Xinxiang 453007, China.

Funding

National Natural Science Foundation of China 32170424Natural Sciences Foundation for Excellent Young Scholar of Henan 222300420052

6 · The paper itself

Abstract

Microcystin-LR (MC-LR), produced by Cyanobacteria, is being detected in many types of waters, posing a universal threat to aquatic animals. However, there have been few comprehensive endpoints assessed, including oxidative stress, transcriptome changes, intestinal microbiota, and histopathology, in anurans exposed to MC-LR. In this study, all these effects of MC-LR on Chinese brown frog (

Indexed as

histopathologyintestinal microbiotaliver transcriptomeMC-LRoxidative stressRana chensinensis tadpoles

Identifiers

PMID41594506

DOI10.3390/ani16020316

PMCPMC12837403

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.