ArticleAnimals : an open access journal from MDPI2026
Analysis of Migration and Adaptive Evolution in Tibetan Sheep Populations.
Wentao Zhang, Chao Yuan, Tingting Guo, Bowen Chen, Fan Wang, Jianbin Liu, Zengkui Lu
Abstract read
In one paragraphArticle in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
7 authors.
Wentao ZhangKey Laboratory of Animal Genetics and Breeding on Tibetan Plateau, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.
Chao YuanKey Laboratory of Animal Genetics and Breeding on Tibetan Plateau, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.ORCID 0000-0003-1403-7675 Tingting GuoKey Laboratory of Animal Genetics and Breeding on Tibetan Plateau, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.ORCID 0000-0003-4472-5444 Bowen ChenKey Laboratory of Animal Genetics and Breeding on Tibetan Plateau, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.
Fan WangCollege of Life Science and Engineering, Northwest Minzu University, Lanzhou 730030, China.
Jianbin LiuKey Laboratory of Animal Genetics and Breeding on Tibetan Plateau, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.ORCID 0000-0001-6550-9236 Zengkui LuKey Laboratory of Animal Genetics and Breeding on Tibetan Plateau, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.ORCID 0000-0002-5993-1083 Funding
Central Public-interest Scientific Institution Basal Research Fund 1610322024012Innovation Project of Chinese Academy of Agricultural Sciences 25-LZIHPS-07Key R&D Program in Gansu Province 24YFNA022Key Talents Program of Gansu Province 2024RCXM60Kunlun Talents·High-End Innovative and Entrepreneurial Talents Program of Qinghai Province QHKLYC-GDCXCY-2024-300National Key R&D Program of China 2022YFD1302102National Technical System for Wool Sheep Industry CARS-39-02
6 · The paper itselfAbstract
The genetic basis for Tibetan sheep adaptation to different high-altitude environments remains unknown. This study conducted whole-genome resequencing on 80 Tibetan sheep individuals from four major distribution areas on the Qinghai-Tibet Plateau. Based on the high-quality single-nucleotide polymorphisms (SNPs) obtained, an analysis of population-level genomic selection signals was performed. Population genomic analysis revealed that Tibetan sheep distributed across China originated in northern China but showed evidence of gene flow from South Asian sheep. Between populations from extremely high-altitude and mid-altitude regions, selection analyses identified five strongly positive selected genes (
Indexed as
cold and drought environmenthyper-arid environmentselection signatureTibetan sheepultra-high altitude environmentwhole-genome resequencing
Identifiers
PMID41594504
PMCPMC12837694
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