Evidence map›Paper›PMID 41594452›Full record

ArticleAnimals : an open access journal from MDPI2026

Effect of Dietary Supplementation with Rumen-Protected GABA (γ-Aminobutyric Acid) on Milk Productivity and Blood Profiles of Dairy Cattle Under Heat Stress Conditions.

Young Hye Joo, Jun Sik Woo, Honggu Lee, Won Seob Kim, Keun Kyu Park, Yognjun Choi

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Young Hye JooDepartment of Marketing, Milae Bioresources Co., Ltd., Seoul 05836, Republic of Korea.ORCID 0000-0003-2511-1084
Jun Sik WooCentral Research Institute, Harim Co., Ltd., Daejeon 08793, Republic of Korea.ORCID 0000-0003-2201-4502
Honggu LeeDepartment of Animal Science and Technology, Konkuk University, Seoul 05029, Republic of Korea.ORCID 0000-0002-0679-5663
Won Seob KimDepartment of Animal Resources, Daegu University, Daegu 38453, Republic of Korea.ORCID 0000-0002-0234-5665
Keun Kyu ParkDepartment of Animal Science and Technology, Konkuk University, Seoul 05029, Republic of Korea.ORCID 0000-0002-8328-3522
Yognjun ChoiSchool of Animal Life Convergence Science, HanKeung National University, Anseong 17579, Republic of Korea.ORCID 0000-0002-5759-4108

Funding

Rural Development Administration RS-2024-00399164
6 · The paper itself

Abstract

This study was conducted to evaluate the effect of rumen-protected γ-aminobutyric acid (GABA) supplementation on milk productivity of lactating Holstein cows. Eighteen Holstein dairy cows (mean parity, 2.2 ± 1.0 year; mean milk yield, 34.3 ± 5.5 kg) were selected in a commercial dairy farm for the experiment. The experiment was conducted from 17 July 2024 to 11 September 2024 (56 days). Generally, THI 72 is set as a threshold since the productivity of Holstein cows starts to decrease. Animals were exposed to heat stress conditions (THI ≥ 72) during the experimental period. The basal diet was fed as a total mixed ration (TMR), and GABA was top-dressed onto the TMR. The treatments were basal diet (Control), basal diet supplemented with rumen-protected GABA 3 g/d (Treatment 1), and basal diet supplemented with rumen-protected GABA 6 g/d (Treatment 2) as a completely randomized design. Statistical significance was compared between the control and GABA treatment groups using the method of repeated measurement. Increased levels of rumen-protected GABA supplementation tended to mitigate the decline in milk yield associated with heat stress (

Indexed as

blood profilesheat stresslactating dairy cowmilk productivityrumen-protected γ-aminobutyric acid

Identifiers

PMID41594452
PMCPMC12837375

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.