Evidence map›Paper›PMID 41594212›Full record

ReviewDiagnostics (Basel, Switzerland)2026

Biomarkers for Predicting Malignant Transformation of Premalignant Lesions of the Larynx: A Systematic Review.

Juan P Rodrigo, Reydson Alcides de Lima-Souza, Fernando López, Göran Stenman, Abbas Agaymy, Miquel Quer, Vinidh Paleri, Ilmo Leivo, Alfons Nadal, Nina Zidar and 4 more

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Juan P RodrigoDepartment of Otolaryngology, Hospital Universitario Central de Asturias, University of Oviedo, Instituto de Investigación Sanitaria del Principado de Asturias, Instituto Universitario de Oncología del Principado de Asturias, 33011 Oviedo, Spain.ORCID 0000-0003-3063-0890
Reydson Alcides de Lima-SouzaDepartment of Oral Diagnosis, Faculdade de Odontologia de Piracicaba, Universidade Estadual de Campinas (UNICAMP), Piracicaba 13414-903, SP, Brazil.ORCID 0000-0001-5045-6960
Fernando LópezDepartment of Otolaryngology, Hospital Universitario Central de Asturias, University of Oviedo, Instituto de Investigación Sanitaria del Principado de Asturias, Instituto Universitario de Oncología del Principado de Asturias, 33011 Oviedo, Spain.
Göran StenmanDepartment of Pathology, Sahlgrenska Center for Cancer Research, Sahlgrenska University Hospital, University of Gothenburg, 405 30 Gothenburg, Sweden.ORCID 0000-0003-1017-7363
Abbas AgaymyInstitute of Pathology, University Hospital Erlangen, 91054 Erlangen, Germany.
Miquel QuerDepartment of Otolaryngology, Hospital Santa Creu y Sant Pau, 08041 Barcelona, Spain.ORCID 0000-0003-2563-6729
Vinidh PaleriThe Royal Marsden NHS Foundation Trust, London SW3 6JJ, UK.ORCID 0000-0002-7933-4585
Ilmo LeivoInstitute of Biomedicine, Pathology, University of Turku, Turku University Hospital, 20520 Turku, Finland.
Alfons NadalPathology Department, Clínic Barcelona, Basic Clinical Practice Department, Universitat de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, 08007 Barcelona, Spain.ORCID 0000-0002-5366-093X
Nina ZidarInstitute of Pathology, Faculty of Medicine, University of Ljubljana, Korytkova 2, 1000 Ljubljana, Slovenia.ORCID 0000-0001-6866-3220
Fernanda V MarianoDepartment of Pathology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas 13083-970, SP, Brazil.
Henrik HellquistDepartment of Biomedical Sciences and Medicine, Algarve Biomedical Center Research Institute, University of Algarve, 8005-139 Faro, Portugal.ORCID 0009-0000-9998-8212
Nina GaleInstitute of Pathology, Faculty of Medicine, University of Ljubljana, Korytkova 2, 1000 Ljubljana, Slovenia.
Alfio FerlitoInternational Head and Neck Scientific Group, 35100 Padua, Italy.ORCID 0000-0002-8247-8002

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biomarkerslaryngeal dysplasiamalignant transformationpremalignant lesionsROBINS-Isystematic review

Identifiers

PMID41594212
PMCPMC12840134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.