Evidence map›Paper›PMID 41593854›Full record

SynthesisInnovations (Philadelphia, Pa.)

Axillary Versus Sternotomy Access in Minimally Invasive Mitral Valve Surgery: A Systematic Review and Meta-Analysis.

Abdullah Almehandi, Mohammed Ramadhan, Yahya Ali, Abdulaziz Almhanedi, Abdulrahman Osama Al-Naseem, Ahmad Gonnah, Ahmad Awad, Johannes Fischer, Hristo Kirov, Torsten Doenst and 2 more

Abstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in Innovations (Philadelphia, Pa.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Abdullah AlmehandiDepartment of Cardiovascular Science, University College London, UK.ORCID 0009-0005-8407-1731
Mohammed RamadhanDepartment of Surgery, Jaber Al Ahmad Al Jaber Al Sabah Hospital, Surra, Al Asimah Governorate, Kuwait.
Yahya AliFaculty of Life Science and Medicine, Kings College London, UK.
Abdulaziz AlmhanediDepartment of Surgery, Jaber Al Ahmad Al Jaber Al Sabah Hospital, Surra, Al Asimah Governorate, Kuwait.
Abdulrahman Osama Al-NaseemDepartment of Surgery, Jaber Al Ahmad Al Jaber Al Sabah Hospital, Surra, Al Asimah Governorate, Kuwait.
Ahmad GonnahImperial College Healthcare NHS Trust, London, UK.
Ahmad AwadFaculty of Medicine, Ain Shams University, Cairo, Egypt.ORCID 0000-0001-6647-1866
Johannes FischerDepartment of Cardiothoracic Surgery, Friedrich-Schiller-University Jena, Germany.
Hristo KirovDepartment of Cardiothoracic Surgery, Friedrich-Schiller-University Jena, Germany.
Torsten DoenstDepartment of Cardiothoracic Surgery, Friedrich-Schiller-University Jena, Germany.
Rakan I NazerDepartment of Cardiac Science, King Fahad Cardiac Centre, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Tulio CaldonazoDepartment of Cardiothoracic Surgery, Friedrich-Schiller-University Jena, Germany.ORCID 0000-0001-5697-2659

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMinimally invasive cardiac surgery for mitral valve (MV) disease is a rising strategy. Axillary access is linked to reduced pain and faster recovery, but its efficacy and safety compared with median sternotomy for MV surgery (MVS) remain unclear. We conducted a meta-analysis comparing the clinical outcomes of MVS via axillary access and median sternotomy.

methodsFour databases were analyzed. The primary endpoint was perioperative mortality. Secondary endpoints included cardiopulmonary bypass (CPB) and cross-clamp times, rethoracotomy, wound complications, mechanical ventilation duration, stroke, hospital and intensive care unit (ICU) stay, and residual moderate mitral regurgitation. A random-effects model was used.

resultsWe included 2,129 patients from 4 studies, with 1,135 (53.3%) undergoing axillary access. Perioperative mortality was comparable between approaches (odds ratio [OR] = 0.34, 95% confidence interval [CI]: 0.09 to 1.23,

conclusionsAxillary access for MVS shows comparable mortality to median sternotomy, with benefits in wound complications, ventilation, and recovery but longer CPB times. Further research is needed to confirm long-term safety and efficacy.

Indexed as

AxillaMinimally Invasive Surgical ProceduresMitral ValveSternotomyCardiopulmonary BypassFemaleHumansLength of StayMaleMitral Valve InsufficiencyPostoperative ComplicationsTreatment Outcomeaxillary accessmedian sternotomyminimally invasive mitral valve surgery

Identifiers

PMID41593854
PMCPMC13049218

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.