Evidence map›Paper›PMID 41593744›Full record

ArticleJournal of nanobiotechnology2026

OCTN2-targeted and ROS-responsive hybrid polymeric micelles for oral delivery of docetaxel.

Haihan Sun, Jingxin Gou, Xiaoshuang Bi, Jiayin Song, Boyuan Liu, Xiaoyu Jin, Bowen Sui, Xiangqun Jin

Abstract read
In one paragraph

Article in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Haihan SunSchool of Pharmaceutical Sciences, Jilin University, No. 1266, Fujin Road, Changchun, 130021, China.
Jingxin GouSchool of Pharmaceutical Sciences, Shenyang Pharmaceutical University, No. 103, Wenhua Road, Shenyang, 110016, China.
Xiaoshuang BiSchool of Pharmaceutical Sciences, Shenyang Pharmaceutical University, No. 103, Wenhua Road, Shenyang, 110016, China.
Jiayin SongSchool of Pharmaceutical Sciences, Shenyang Pharmaceutical University, No. 103, Wenhua Road, Shenyang, 110016, China.
Boyuan LiuSchool of Pharmaceutical Sciences, Shenyang Pharmaceutical University, No. 103, Wenhua Road, Shenyang, 110016, China.
Xiaoyu JinSchool of Pharmaceutical Sciences, Changchun University of Chinese Medicine, Changchun, 130117, China.
Bowen SuiNortheast Asia Research Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, 130117, China. suibowen@163.com.
Xiangqun JinSchool of Pharmaceutical Sciences, Jilin University, No. 1266, Fujin Road, Changchun, 130021, China. jinxq@jlu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our previous research identified that an oral mPEG-b-PCL polymeric micelle (PM) maintained satisfactory integrity but exhibited limited transcytosis efficiency. To enhance transcytosis and enable ROS-responsive release, we developed a series of hybrid PMs by blending a synthesized L-carnitine-grafted, thioketal-linked LC-PEG

Indexed as

DocetaxelDrug CarriersMicellesPolymersReactive Oxygen SpeciesAdministration, OralAnimalsAntineoplastic AgentsCaco-2 CellsCell Line, TumorFemaleHumansMiceMice, Inbred BALB CParticle SizePolyestersAntineoplastic AgentsDocetaxelDrug CarriersMicellesPolyestersPolyethylene GlycolsPolymersReactive Oxygen SpeciesBreast cancerDocetaxelOCTN2-targetedOral deliveryPolymeric micelleROS-responsive

Identifiers

PMID41593744
PMCPMC12918599

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.