Evidence map›Paper›PMID 41593570›Full record

SynthesisBMC pulmonary medicine2026

The effect of respiratory training on lung function in intensive care unit patients: a systematic review and meta-analysis.

Hejin Yang, Hui Huang, Wenjuan Dai, Lizhu Wei, Miao Huang, Lihong Yuan

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC pulmonary medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hejin Yang *Department of Rehabilitation Medicine, Ganzhou People's Hospital, Ganzhou, China.
Hui Huang *Department of Rehabilitation Medicine, Ganzhou People's Hospital, Ganzhou, China.
Wenjuan DaiDepartment of Rehabilitation Medicine, Ganzhou People's Hospital, Ganzhou, China.
Lizhu WeiDepartment of Rehabilitation Medicine, Ganzhou People's Hospital, Ganzhou, China.
Miao HuangDepartment of Rehabilitation Medicine, Ganzhou People's Hospital, Ganzhou, China. 1791203741@qq.com.
Lihong YuanDepartment of Rehabilitation Medicine, Ganzhou People's Hospital, Ganzhou, China. 294637109@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMechanically ventilated patients in the intensive care unit (ICU) usually develop respiratory muscle wasting atrophy, causing pulmonary dysfunction. The benefits of respiratory muscle training (RMT) on pulmonary function recovery have been demonstrated, but whether it is effective in patients following mechanical ventilation in the ICU has not been proven. This study aimed to evaluate the effectiveness of RMT on lung function and mechanical ventilation duration in ICU patients, addressing the lack of comprehensive evidence on its benefits for mechanically ventilated individuals.

methodsThis systematic review and meta-analysis was conducted on the databases from PubMed, Cochrane Library, Web of Science, and Embase. The search period was extended to 30th April 2025. Studies included ICU patients receiving RMT, and outcomes such as maximum inspiratory pressure (MIP), forced vital capacity (FVC), and mechanical ventilation duration were analyzed using RevMan software. Heterogeneity was assessed using I² statistics.

results18 randomized controlled trials (RCTs) were included for analysis. RMT significantly improved MIP (SMD: 0.88, 95% CI: 0.53–1.24) and FVC (SMD: 0.32, 95% CI: 0.07–0.58) and reduced mechanical ventilation duration by 0.88 days (95% CI: -1.10 to -0.66).

conclusionsRespiratory muscle training enhances lung function and shortens mechanical ventilation duration in ICU patients, supporting its early implementation as a rehabilitation strategy.

Indexed as

Breathing ExercisesLungRespiration, ArtificialRespiratory MusclesHumansIntensive Care UnitsRandomized Controlled Trials as TopicVital CapacityExerciseIntensive care unitLung functionMechanical ventilationRespiratory muscles

Identifiers

PMID41593570
PMCPMC12918567

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.