Evidence map›Paper›PMID 41593323›Full record

ArticleScientific reports2026

Unveiling economic and humanistic burden of hematologic malignancies in Japan with personal health record data.

Saaya Tsutsué, Kenshi Suzuki, Sooyeol Lim, Ryosuke Nishi, Honoka Nakamura, Hiroya Asou, Anila Mathew, Takunari Yoshinaga

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Saaya TsutsuéGilead Sciences Japan, 1-9-2 Marunouchi, Chiyoda-ku, Tokyo, 100-6616, Japan. saayatsutsue@icloud.com.
Kenshi SuzukiJapanese Red Cross Medical Center, Tokyo, Japan.
Sooyeol LimINTAGE Healthcare, Tokyo, Japan.
Ryosuke NishiINTAGE Healthcare, Tokyo, Japan.
Honoka NakamuraINTAGE Healthcare, Tokyo, Japan.
Hiroya AsouGilead Sciences Japan, 1-9-2 Marunouchi, Chiyoda-ku, Tokyo, 100-6616, Japan.
Anila MathewGilead Sciences Japan, 1-9-2 Marunouchi, Chiyoda-ku, Tokyo, 100-6616, Japan.
Takunari YoshinagaGilead Sciences Japan, 1-9-2 Marunouchi, Chiyoda-ku, Tokyo, 100-6616, Japan. Takunari.Yoshinaga@gilead.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To characterize the economic and humanistic burden of patients with hematologic malignancies in Japan using real-world data. Patients with a claim record for a hematologic malignancy who responded to a survey regarding productivity loss and quality of life (QoL) were analyzed to assess their direct medical cost, productivity loss, and QoL along with their levels of comorbidity. This study identified a main cohort of 122 patients with a hematologic malignancy who responded to Work Productivity and Activity Impairment (WPAI) and EQ-5D-5 L questionnaires. Median patient age was 54.5 years (range 25–71 years), with median Charlson Comorbidity Score (CCI) of 2. Most of the mean total cost (USD 12,836.14; JPY 1,670,624) was attributed to productivity loss (mean USD 8,106.39; JPY 1,055,046) rather than direct medical cost (mean USD 4,729.76; JPY 615,578). Presenteeism (mean USD 5,117.84; JPY 666,086) accounted for a greater proportion of productivity loss than absenteeism (mean USD 2,988.55; JPY 388,960). Deterioration in QoL (-0.045) was observed in comparison to the general population in Japan. The results point to the need for a social security policy to provide appropriate support such as better therapies or access for patients who must receive treatment while still working.

Indexed as

Cost of IllnessHealth Records, PersonalHematologic NeoplasmsAbsenteeismAdultAgedEfficiencyFemaleHealth Care CostsHumansJapanMaleMiddle AgedQuality of LifeSurveys and QuestionnairesCostDatabase studyHematological malignancyJapanProductivity lossQuality of life

Identifiers

PMID41593323
PMCPMC12909960

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.