Evidence map›Paper›PMID 41593055›Full record

ArticleNature communications2026

Abiotic sugar enantiomers in the CI carbonaceous chondrite Orgueil.

Vanessa Leyva, Manuel Robert, Raphaël Pepino, Jana Bocková, Cornelia Meinert

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vanessa Leyva *Université Côte d'Azur, Institut de Chimie de Nice, UMR 7272 CNRS, Nice, France.
Manuel Robert *Université Côte d'Azur, Institut de Chimie de Nice, UMR 7272 CNRS, Nice, France.ORCID http://orcid.org/0009-0004-5973-8429
Raphaël PepinoUniversité Côte d'Azur, Institut de Chimie de Nice, UMR 7272 CNRS, Nice, France.
Jana BockováUniversité Côte d'Azur, Institut de Chimie de Nice, UMR 7272 CNRS, Nice, France.ORCID http://orcid.org/0000-0003-3807-2491
Cornelia MeinertUniversité Côte d'Azur, Institut de Chimie de Nice, UMR 7272 CNRS, Nice, France. Cornelia.MEINERT@univ-cotedazur.fr.ORCID http://orcid.org/0000-0002-7256-2112

Funding

EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 101170457-ICE-EEVOLVE
6 · The paper itself

Abstract

The uneven detection of prebiotic organic compounds in meteorites-where amino acids and nucleobases are commonly identified but sugars remain rare and poorly characterized-limits our understanding of extraterrestrial organic chemistry. This discrepancy is striking given that laboratory simulations of interstellar ice chemistry readily produce complex sugars. Here we report the simultaneous analysis of sugar and amino acid enantiomers in a meteorite sample. Multiple aldoses were detected in the Orgueil meteorite, including ribose, arabinose, xylose, lyxose, and the ketopentose ribulose, several of which display near-racemic distributions consistent with an extraterrestrial origin. Recovery experiments demonstrate that sugar abundances are severely underestimated. Despite this limitation, pentose abundances are comparable to those of some C4-C5 amino acid enantiomers, implying higher true concentrations. These results indicate efficient abiotic sugar formation in space and suggest that meteorites may have delivered a broader range of prebiotically relevant sugars to early Earth than previously recognized.

Identifiers

PMID41593055
PMCPMC12949004

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.