Evidence map›Paper›PMID 41593047›Full record

ReviewMicrosystems & nanoengineering2026

Sensitivity enhancement of surface plasmon resonance biosensors based on versatile nanostructures: principle, fabrication, and illustrative applications.

Xiantong Yu, Yufeng Yuan, Jun Zhou, Min Chang, Shuwen Zeng, Songlin Zhuang

Abstract readReview
In one paragraph

Review in Microsystems & nanoengineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiantong YuKey Laboratory of Optical Technology and Instrument for Medicine, Ministry of Education, College of Optical-Electrical and Computer Engineering, University of Shanghai for Science and Technology, Shanghai, China. xtyu@usst.edu.cn.
Yufeng YuanSchool of Electronic Engineering and Intelligentization, Dongguan University of Technology, Dongguan, China. yufengyuan@dgut.edu.cn.ORCID http://orcid.org/0000-0001-7472-4368
Jun ZhouKey Laboratory of Optical Technology and Instrument for Medicine, Ministry of Education, College of Optical-Electrical and Computer Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Min ChangKey Laboratory of Optical Technology and Instrument for Medicine, Ministry of Education, College of Optical-Electrical and Computer Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Shuwen ZengLight, Nanomaterials, Nanotechnologies (L2n), CNRS UMR 7076, University of Technology of Troyes, Troyes, France. shuwen.zeng@cnrs.fr.
Songlin ZhuangKey Laboratory of Optical Technology and Instrument for Medicine, Ministry of Education, College of Optical-Electrical and Computer Engineering, University of Shanghai for Science and Technology, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surface plasmon resonance (SPR) biosensoris a new type of high sensitivity, real-time, label-free detection technology, which plays an increasingly important role in the biomedicine field. Considering the urgent requirement of trace detection, especially for diagnosing early-stage diseases, the demand for high detection sensitivity of sensors is increasing. In recent years, various nanostructures have been proposed to design SPR biosensors. By constructing composite nanostructures, the detection sensitivity has been significantly enhanced, which has become a promising solution to expand the application of SPR biosensors. This review systematically summarized the basic principle, fabrication and illustrative application of SPR biosensors based on versatile nanostructures. Firstly, the mechanisms of various nanostructures to enhance the detection sensitivity of SPR biosensors were clarified. Then, the preparation strategies of various nanostructures were comprehensively illustrated. In addition, this review also summarized the latest applications of SPR biosensors with different structures. Finally, this review carefully highlighted the current challenges and possible development directions in future.

Identifiers

PMID41593047
PMCPMC12848061

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.