Evidence map›Paper›PMID 41593018›Full record

ArticleAging & mental health2026

The long-term impact of adverse childhood experiences on episodic memory in mid- to late-life among US older adults.

Kimson E Johnson, Monique J Brown

Abstract read
In one paragraph

Article in Aging & mental health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Kimson E JohnsonInstitute for Social Research, Survey Research Center, University of Michigan, Ann Arbor, MI, USA.
Monique J BrownDepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Enhancing Retrospective Life History Data in the Health and Retirement Study- RenewalR01AG051142 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SMITH, JACQUI · 2015 to 2023
$8.1M
Optimizing PrEP uptake for African American women in the South by empowering women to make informed HIV prevention and sexual health choicesR34MH137775 · NIMH · UNIVERSITY OF GEORGIA · PI BROWN, MONIQUE JANIEL, HAIDER, MOHAMMAD RIFAT · 2024 to 2024
$633k
NIA NIH HHS L60 AG089736NIA NIH HHS R01 AG051142NIA NIH HHS U01 AG009740NIMH NIH HHS R34 MH137775
6 · The paper itself

Abstract

objectivesAdverse childhood experiences (ACEs), including abuse, neglect, and household dysfunction, are associated with depression, substance use. While, prior research suggests ACEs influence memory, few studies have examined this relationship in a nationally representative sample of older US adults. This study explores associations between ACEs before 18 and mid- to late-life episodic memory.

methodsWe conducted a secondary analysis of Health and Retirement Study data to assess ACEs and episodic memory in adults aged 51 and older. ACEs were measured as cumulative exposure to early adversity (repeating school, trouble with police, parental substance use, physical abuse). Episodic memory was assessed using total recall (immediate + delayed word recall). Group differences were examined using t-tests and chi-square tests. Linear regression models tested associations between ACE exposure (0, 1, 2, ≥3) and memory scores, adjusting for sociodemographic, childhood, and psychosocial factors.

resultsAmong 7568 participants, 2,768 (36.9%) reported ≥1 ACE; 187 (2.5%) reported ≥3. The mean total recall score was 10.31 ± 3.70. Exposure to ≥3 ACEs was associated with lower memory scores (

conclusionsExperiencing ≥3 ACEs before 18 was linked to poorer episodic memory, underscoring the value of trauma-informed strategies to support brain health.

Indexed as

Adverse Childhood ExperiencesAgingMemory, EpisodicAgedAged, 80 and overFemaleHumansMaleMental RecallMiddle AgedUnited StatesAdverse childhood experiencesagingepisodic memorymemory

Identifiers

PMID41593018
PMCPMC12990772

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.