Evidence map›Paper›PMID 41592845›Full record

ArticleBMJ open2026

Bridging the gap in the UK's National Health Service integrated care systems: insights from a mixed methods implementation evaluation of UCLP-PRIMROSE, a care innovation to reduce physical health inequalities for people with severe mental illness.

Philippa Shaw, Zuneera Khurshid, Danielle Lamb, Fiona A Stevenson, Gregor Russell, Kristian Hudson, Nirandeep Rehill, Gemma Copsey, Matt Kearney, Edward Beveridge and 2 more

Abstract read
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Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

12 authors.

Philippa ShawDivision of Psychiatry, University College London, London, England, UK philippa.shaw@ucl.ac.uk.ORCID http://orcid.org/0009-0000-2180-9501
Zuneera KhurshidImprovement Academy, Bradford Institute for Health Research, Bradford, England, UK.
Danielle LambDepartment of Primary Care and Population Health, University College London, London, England, UK.ORCID http://orcid.org/0000-0003-1526-9793
Fiona A StevensonPrimary Care and Population Health, Royal Free Campus, University College London, London, England, UK.ORCID http://orcid.org/0000-0003-2139-2309
Gregor RussellBradford District Care NHS Foundation Trust, Saltaire, England, UK.
Kristian HudsonImprovement Academy, Bradford Institute for Health Research, Bradford, England, UK.
Nirandeep RehillDepartment of Primary Care and Population Health, University College London, London, England, UK.ORCID http://orcid.org/0000-0003-4179-0996
Gemma CopseyUCLPartners, London, England, UK.
Matt KearneyUCLPartners, London, England, UK.
Edward BeveridgeUCLPartners, London, England, UK.
Ian PrenelleNorth London NHS Foundation Trust, London, UK.
David OsbornDivision of Psychiatry, University College London, London, England, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to determine whether UCLP-PRIMROSE (a care innovation to reduce physical health inequalities for people with severe mental illness) could be set up in the current UK National Health Service (NHS) context and identify the processes, barriers and facilitators to implementation.

designWe employed a convergent mixed methods approach, combining interviews, ethnographic site visits and the collection of meeting notes and uptake data for core model components. Interview transcripts were analysed using reflexive thematic analysis, and all qualitative data, including interview transcripts, were analysed using the Consolidated Framework for Implementation Research. Qualitative work and insights from implementation uptake frequencies were integrated using Normalisation Process Theory.

settingWe evaluated implementation in Yorkshire and three London boroughs, mainly within general practices.

participantsWe conducted interviews with 39 staff members who were implementing and/or delivering UCLP-PRIMROSE.

interventionUCLP-PRIMROSE is an integrated evidence-based care pathway developed to reduce cardiovascular disease risk and mental health relapse in people with severe mental illness.

resultsAdaptation and delivery varied in completeness and consistency across 24 general practices and their wider care teams. Factors outside the implementation teams' influence challenged the embedding of UCLP-PRIMROSE. Factors included the impact from the immaturity of NHS integrated care systems, unintended consequences of the incentivised NHS severe mental illness physical health check and limited capacity for implementing in a system facing resourcing challenges. Drivers of successful implementation included staff being aligned with the values of the UCLP-PRIMROSE model and system leaders acting as champions. Supportive foundational processes acted as facilitators: these included protected and prioritised time for reflection, learning and problem solving.

conclusionsImplementation of UCLP-PRIMROSE was moderately successful in a relatively short period of time. At the end of the research, all teams wanted to sustain delivery. However, further pathway simplification and additional resources are required to spread UCLP-PRIMROSE beyond early pockets of good practice.

Indexed as

Cardiovascular DiseasesDelivery of Health Care, IntegratedHealth Status DisparitiesMental DisordersState MedicineHumansQualitative ResearchUnited KingdomCardiovascular DiseaseImplementation SciencePrimary Health CareSchizophrenia & psychotic disorders

Identifiers

PMID41592845
PMCPMC12853453

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.