Evidence map›Paper›PMID 41592760›Full record

ArticleProceedings. Biological sciences2026

Interepidemic Rift Valley fever in East Africa: the recent risk landscape and projected impacts of global change.

Evan A Eskew, Erin Clancey, Deepti Singh, Silvia Situma, Luke Nyakarahuka, M Kariuki Njenga, Scott L Nuismer

Abstract read
In one paragraph

Article in Proceedings. Biological sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Evan A EskewInstitute for Interdisciplinary Data Sciences, University of Idaho, Moscow, ID, USA.ORCID 0000-0002-1153-5356
Erin ClanceyPaul G. Allen School for Global Health, Washington State University, Pullman, WA, USA.ORCID 0000-0003-4728-4023
Deepti SinghSchool of the Environment, Washington State University, Vancouver, WA, USA.
Silvia SitumaGlobal Health-Kenya, Washington State University, Nairobi, Kenya.
Luke NyakarahukaDepartment of Biosecurity, Ecosystems and Veterinary Public Health, Makerere University, Kampala, Uganda.
M Kariuki NjengaPaul G. Allen School for Global Health, Washington State University, Pullman, WA, USA.
Scott L NuismerDepartment of Biology, University of Idaho, Moscow, ID, USA.ORCID 0000-0001-9817-0056

Funding

Emerging Infectious Diseases Research Center - East and Central AfricaU01AI151799 · NIAID · WASHINGTON STATE UNIVERSITY · PI M KARIUKI NJENGA · 2020 to 2026
$10.4M
COLLABORATIVE RESEARCH: A MATHEMATICAL THEORY OF TRANSMISSIBLE VACCINES R01GM122079 · NIGMS · UNIVERSITY OF IDAHO · PI SCOTT L NUISMER · 2016 to 2026
$2.2M
Zoonotic and Emerging Infectious Diseases Training ProgramD43TW011519 · FIC · WASHINGTON STATE UNIVERSITY · PI Walter Godfrey Jaoko, Thumbi Mwangi · 2020 to 2026
$1.2M
Coalition for Epidemic Preparedness InnovationsFIC NIH HHS D43 TW011519National Institute of Allergy and Infectious DiseasesNIAID NIH HHS U01 AI151799NIGMS NIH HHS R01 GM122079
6 · The paper itself

Abstract

Rift Valley fever (RVF) is a zoonotic disease that causes sporadic, multi-country epidemics. However, there is limited understanding of RVF virus circulation during interepidemic periods and the potential impacts of global change on interepidemic RVF. To address these knowledge gaps, we built a predictive model using recent interepidemic RVF outbreak data from Kenya, Tanzania and Uganda. We then projected interepidemic RVF risk for three future time periods (2021-2040, 2041-2060, 2061-2080) under three global change scenarios representing different trajectories for climate and human population distribution (SSP126, SSP245, SSP370). Our model identified interepidemic RVF risk hotspots in east Kenya, east Tanzania and southwest Uganda. Hydrology was a major driver of disease risk: hotspots emerged in association with lakes and rivers, and risk peaked during May-July following the long rains season (March-May). Projections under global change scenarios suggested that disease risk will generally decrease over time. Nevertheless, owing to expected human population growth, we estimate that > 90 million people in the study region will be exposed to interepidemic RVF by 2061-2080, which is nearly double the historical (1970-2000) estimate of approximately 49 million people. Mitigating the future health impacts of RVF will require increased disease surveillance, prevention and control effort in risk hotspots.

Indexed as

Climate ChangeRift Valley FeverAfrica, EasternAnimalsDisease OutbreaksHumansKenyaTanzaniaUgandaclimate changeemerging infectious diseaseforce of infectionmachine learningmosquito-borne diseasepopulation growthserologyshared socioeconomic pathwaysvector-borne diseasezoonosis

Identifiers

PMID41592760
PMCPMC13334827

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.