ArticleAllergy, asthma & immunology research2026
Newborn Transepidermal Water Loss and Gestational Age as Predictive Factors for Infant Atopic Dermatitis in the First Three Months of Age.
Article in Allergy, asthma & immunology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
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3 authors.
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Abstract
purposeTransepidermal water loss (TEWL) and stratum corneum hydration (SCH) are commonly used to assess epidermal barrier hydration. We investigated the associations of TEWL and SCH levels in newborns and the incidence of atopic dermatitis (AD) within the first 3 months of age.
methodsWe measured SCH and TEWL levels on the cheeks of 330 healthy full-term Vietnamese newborns within 48 hours after birth using a GPSkin Barrier Pro
resultsA total of 233 newborns were followed up during the first 3 months of age, of whom 29 (12.4%) were diagnosed with AD. An increased risk of AD development was associated with higher TEWL levels within 48 hours after birth (adjusted risk ratio [aRR], 1.31; 95% confidence interval [CI], 1.14-1.51;
conclusionsThe TEWL levels and gestational age within 48 hours after birth could serve as predictive factors for the development of AD in the first 3 months of life. This finding establishes a basis for the development of optimal prevention methods for AD.
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