ArticlePloS one2026
Association between delirium and neutrophil percentage-to-albumin ratio in patients with cervical spinal cord injury: A single-center, retrospective study.
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designSingle-center, case-control study.
objectiveThis study investigated if the neutrophil percentage-to-albumin ratio (NPAR) could predict the onset of delirium in patients with cervical spinal cord injury (CSCI).
backgroundDelirium is a common and serious complication in patients with CSCI, leading to prolonged hospitalization and adverse clinical outcomes. Several risk factors have been identified, but the role of hematologic biomarkers in predicting delirium has remained unclear. While NPAR is a potential marker of systemic inflammation, its association with delirium in CSCI patients has not been established.
methodsThe analysis included 147 patients with acute CSCI who were admitted to a single tertiary emergency center between 2010 and 2023. Delirium was diagnosed based on the Diagnostic and Statistical Manual of Mental Disorders, Fourth or Fifth Edition criteria. Clinical characteristics, laboratory data, and patient outcomes were compared between those with and without delirium. The association between NPAR and delirium was assessed using receiver operating characteristic (ROC) curve analysis and logistic regression models.
resultsThe incidence of delirium was 10.2% (15/147 patients). ROC analysis identified an NPAR cutoff value of 22 on the day of injury, with an AUC of 0.672. Multivariate logistic regression analysis revealed that an NPAR ≥22 (OR: 7.703, 95% CI: 2.151-27.584, P = .002) was independent risk factors for delirium.
conclusionWe found a significant association between a high NPAR (≥22) on the day of injury and the onset of delirium in CSCI patients. NPAR may be an accessible and effective biomarker for early delirium prediction, allowing timely interventions to improve patient outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.