ArticleProceedings of the National Academy of Sciences of the United States of America2026
Soluble adenylyl cyclase in nonmammalian sperm is directly controlled by pH, not by HCO
Olivia Kendall, Oanh Tu Hoang, Joshua L Wort, Hussein Hamzeh, Heinz G Körschen, René Pascal, Kai Korsching, Meritxell Wu-Lu, Wolfgang Bönigk, Christian Kambach and 5 more
Abstract read
In one paragraphArticle in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
15 authors.
Olivia KendallMax Planck Institute for Neurobiology of Behavior-caesar, Molecular Sensory Systems Group, Bonn 53175, Germany.ORCID 0009-0002-1481-4227 Oanh Tu HoangDepartment of Chemistry, Faculty II, Technical University Berlin, Berlin 10623, Germany.
Joshua L WortLife and Medical Sciences Institute, Molecular Sensory Systems, University of Bonn, Bonn 53115, Germany.ORCID 0009-0001-9162-0429 Hussein HamzehMax Planck Institute for Neurobiology of Behavior-caesar, Molecular Sensory Systems Group, Bonn 53175, Germany.
Heinz G KörschenMax Planck Institute for Neurobiology of Behavior-caesar, Molecular Sensory Systems Group, Bonn 53175, Germany.
René PascalMax Planck Institute for Neurobiology of Behavior-caesar, Molecular Sensory Systems Group, Bonn 53175, Germany.ORCID 0009-0006-7324-1296 Kai KorschingMax Planck Institute for Neurobiology of Behavior-caesar, Molecular Sensory Systems Group, Bonn 53175, Germany.ORCID 0000-0002-9452-2058 Meritxell Wu-LuDepartment of Chemistry, Faculty II, Technical University Berlin, Berlin 10623, Germany.ORCID 0009-0006-8130-6846 Wolfgang BönigkMax Planck Institute for Neurobiology of Behavior-caesar, Molecular Sensory Systems Group, Bonn 53175, Germany.ORCID 0000-0003-0217-9086 Luis AlvarezMax Planck Institute for Neurobiology of Behavior-caesar, Molecular Sensory Systems Group, Bonn 53175, Germany.ORCID 0000-0002-1027-2291 Reinhard SeifertMax Planck Institute for Neurobiology of Behavior-caesar, Molecular Sensory Systems Group, Bonn 53175, Germany.ORCID 0009-0003-5872-4845 Timo StrünkerMax Planck Institute for Neurobiology of Behavior-caesar, Molecular Sensory Systems Group, Bonn 53175, Germany.ORCID 0000-0003-0812-1547 Maria Andrea MroginskiDepartment of Chemistry, Faculty II, Technical University Berlin, Berlin 10623, Germany.ORCID 0000-0002-7497-5631 U Benjamin KauppMax Planck Institute for Neurobiology of Behavior-caesar, Molecular Sensory Systems Group, Bonn 53175, Germany.ORCID 0000-0002-0696-6397 Funding
Cluster of Excellence UniSysCatDeutsche Forschungsgemeinschaft (DFG) KA 545/15-1Deutsche Forschungsgemeinschaft (DFG) SFB 1078Deutsche Forschungsgemeinschaft (DFG) SPP1726
6 · The paper itselfAbstract
In mammalian sperm, high HCO
Indexed as
Adenylyl CyclasesSalmo salarSea UrchinsSpermatozoaSperm MotilityAmino Acid SequenceAnimalsBicarbonatesCalciumChemotactic FactorsCyclic AMPHEK293 CellsHumansHydrogen-Ion ConcentrationMalePhylogenyAdenylyl CyclasesBicarbonatesCalciumChemotactic FactorsCyclic AMPRecombinant ProteinscAMPfertilizationpHsoluble adenylyl cyclase (sAC)sperm
Identifiers
PMID41591904
PMCPMC12867704
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