Evidence map›Paper›PMID 41591865›Full record

SynthesisThe European journal of general practice2026

Impact of nurse practitioners in primary care on patients with chronic diseases in rural and underserved areas: A systematic review.

Ariane Sacchetti, Mélanie Berube, Christophe Pison, Marc-Aurèle Gagnon, Alexandre Bellier

Abstract readSystematic ReviewReview
In one paragraph

Synthesis in The European journal of general practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ariane SacchettiLaboratoire de Bioénergétique Fondamentale et Appliquée, Univ. Grenoble Alpes, Grenoble, France.
Mélanie BerubeCentre de recherche du CHU de Québec, Axe santé des populations et pratiques optimales en santé, Québec, Canada.
Christophe PisonLaboratoire de Bioénergétique Fondamentale et Appliquée, Univ. Grenoble Alpes, Grenoble, France.
Marc-Aurèle GagnonCentre de recherche du CHU de Québec, Axe santé des populations et pratiques optimales en santé, Québec, Canada.
Alexandre BellierDépartement Universitaire Grenoble Alpes des Patients Enseignants, Univ. Grenoble Alpes, Grenoble, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAgeing, multimorbidity, and workforce shortages increasingly limit access to primary healthcare, especially in rural and underserved areas.

objectivesTo document impact of nurse practitioners (NPs) in primary care on patients with chronic diseases.

methodsSearches were conducted in Medline, EMBASE, CINAHL, and CENTRAL (March 1978-October 2023). This systematic review followed MECIR and PRISMA guidelines (PRISMA 2020 checklist: EQUATOR Network) with SWiM used as a PRISMA extension due to the lack of meta-analysis. The focus was on NPs' roles in chronic disease management and primary care in underserved or remote areas, excluding mental health, cancer, and dental care.

resultsAmong 3,684 citations, 25 studies were selected, including 10 RCT. NPs may improve access to primary care and chronic disease management, particularly in underserved areas. Although not all studies directly compared NPs to traditional models, they were most often assessed against General Practitioners (GPs) alone. Seven studies also evaluated collaborative NP-GP models versus GP-only care. Patient satisfaction was generally higher with NPs, possibly due to longer consultations and greater patient education. Clinical and biological outcomes were often comparable between NPs and GPs, with the best results in collaborative models, which were also associated with higher costs.

conclusionNPs may enhance access to care, particularly for vulnerable populations. Higher patient satisfaction may be linked to longer consultations and patient education. While clinical outcomes were comparable to those of GPs, collaborative models yielded the best results, though potentially at a higher cost.

Indexed as

Medically Underserved AreaNurse PractitionersPrimary Health CareRural Health ServicesChronic DiseaseHealth Services AccessibilityHumansPatient SatisfactionRural Populationaccess to carechronic diseasehealthcare disparitiesNurse practitionersprimary care

Identifiers

PMID41591865
PMCPMC12849805

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.