Evidence map›Paper›PMID 41591727›Full record

ArticlePhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology2026

Properties of Aspalathus linearis extracts as sunscreen agents in combination with standard UV filters.

Jose Aguilera, Pablo Sepúlveda, Ana López Sánchez, Luisa Haya, Salvador González, María Victoria de Gálvez

Abstract read
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In one paragraph

Article in Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. What's New in Photoprotection?American journal of clinical dermatology · 2026
    Review
  2. Potential Value of a Combination ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jose AguileraPhotobiological Dermatology Laboratory, Medical Research Center, Faculty of Medicine, Department of Dermatology and Medicine, University of Málaga, Boulevard Louis Pasteur s/n, E-29071, Malaga, Spain. jaguilera@uma.es.ORCID http://orcid.org/0000-0002-1911-111X
Pablo SepúlvedaPhotobiological Dermatology Laboratory, Medical Research Center, Faculty of Medicine, Department of Dermatology and Medicine, University of Málaga, Boulevard Louis Pasteur s/n, E-29071, Malaga, Spain.
Ana López SánchezInnovation and Development, Cantabria Labs, Madrid, 28043, Spain.
Luisa HayaInnovation and Development, Cantabria Labs, Madrid, 28043, Spain.
Salvador GonzálezDepartment of Medicine and Medical Specialties, Alcalá de Henares University, Madrid, 28805, Spain.
María Victoria de GálvezPhotobiological Dermatology Laboratory, Medical Research Center, Faculty of Medicine, Department of Dermatology and Medicine, University of Málaga, Boulevard Louis Pasteur s/n, E-29071, Malaga, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The new horizons in sunscreen development are based on the discovery of novel active ingredients, and those from natural sources are the most promising. The objective of the work was to analyze the potential of different Aspalathus linearis (AL) extracts as natural photoprotective ingredients to be used in combination with standard UV filters in topical formulas. The impact of AL extracts on different biological protection factors, as well as on the photostability of standard organic UV filters, was measured. Under this aim, and employing in vitro techniques, UV transmittance properties, solar protection factor, UVA protection factor, and immune protection factor were analyzed for the extracts formulated alone or in combination with the UVB and UVA standard filters Octyl-methoxy-cinnamate (OMC) and Butyl-Methoxy-dibenzoyl-methane (BMDBM). Water containing AL extracts showed a significant UV absorbance in the entire UV spectrum with an absorption peak around 285 nm. The addition of AL extracts to sunscreen galenic formulas, including OMC and BMDBM, increased the protection factors up to 50%. AL extracts were also able to protect BMDBM and OMC against photodegradation under increasing radiation doses up to 14.4 standard erythemal doses. In conclusion, the addition of AL extracts in topical photoprotective formulas provides the double benefit of increasing the protection values against different biological effects, as well as improving photostability. Thus, these natural extracts appear as valuable candidates for the development of safer and more efficient sunscreens.

Indexed as

Plant ExtractsSunscreening AgentsUltraviolet RaysCinnamatesHumansPropiophenonesavobenzoneCinnamatesoctylmethoxycinnamatePlant ExtractsPropiophenonesSunscreening AgentsBiological protection factorsBoosterNatural extractsPhotostabilitySolar protection factorSunscreens

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.