Evidence map›Paper›PMID 41591509›Full record

ArticleActa neurochirurgica2026

Wider window, easier access: optimizing Leksell Vantage positioning for posterior fossa stereotactic biopsy.

Chiara Barbesino, Andrea Bianconi, Pietro Fiaschi, Concetta Viola, Gianluigi Zona, Paolo Merciadri

Abstract read
In one paragraph

Article in Acta neurochirurgica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chiara BarbesinoDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genova, Genoa, Italy. s4355056@studenti.unige.it.
Andrea BianconiDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genova, Genoa, Italy.
Pietro FiaschiDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genova, Genoa, Italy.
Concetta ViolaDepartment of Neurosurgery, IRCCS Azienda Ospedaliera Metropolitana di Genova, Genoa, Italy.
Gianluigi ZonaDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genova, Genoa, Italy.
Paolo MerciadriDepartment of Neurosurgery, IRCCS Azienda Ospedaliera Metropolitana di Genova, Genoa, Italy. paolo.merciadri@hsanmartino.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn Neurosurgery, stereotactic biopsy represents the main minimally invasive surgical technique to target deep and hard-to-reach brain sites that are not accessible by traditional surgical methods. The best trajectory for biopsy needle insertion is planned on the basis of CT or MRI studies. According to the relevant literature, although biopsy of the posterior cranial fossa with Leksell® Vantage™ Head Frame is possible, it involves several technical and clinical challenges. We describe an alternative configuration of the Leksell® Vantage™ system that addresses these limitations in the management of posterior cranial fossa lesions.

methodsAt our Department (IRCCS Ospedale Policlinico San Martino in Genoa) we have used Leksell® Vantage™ stereotactic system together with Medtronic StealthStation™ S8 planning software to perform a series of seven stereotactic biopsies in the occipital or cerebellar region by rotating the stereotactic helmet 180° on the axial plane, resulting in an inversion of both the anteroposterior and lateral-lateral axes.

resultsWe demonstrate that stereotactic posterior fossa biopsies can be performed with helmet rotation, without additional procedural complications. No similar approach has previously been described in the literature.

conclusionThis approach significantly enhances access to the posterior cranial fossa and occipital lesions. This optimisation improves manoeuvrability, provides a more advantageous viewing angle for the needle-biopsy trajectory and allows for a less complex preoperative planning. The approach remains minimally invasive and is generally compatible with execution under conscious sedation.

Indexed as

Cranial Fossa, PosteriorStereotaxic TechniquesBiopsyHumansLeksell® Vantage™Posterior fossaStereotactic biopsy

Identifiers

PMID41591509
PMCPMC12852188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.