Evidence map›Paper›PMID 41591147›Full record

ArticleDrug and alcohol review2026

Interrupted Time Series Analysis of Alcohol Use Disorder Treatment Utilisation During the Coronavirus Pandemic in Hamburg, Germany.

Jakob Manthey, Carolin Kilian, Ludwig Kraus, Anna Schranz, Bernd Schulte

Abstract read
In one paragraph

Article in Drug and alcohol review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jakob MantheyCentre for Interdisciplinary Addiction Research, Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0003-1231-3760
Carolin KilianCentre for Interdisciplinary Addiction Research, Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Ludwig KrausCentre for Interdisciplinary Addiction Research, Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Anna SchranzCentre for Interdisciplinary Addiction Research, Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Bernd SchulteCentre for Interdisciplinary Addiction Research, Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0003-1139-030X

Funding

Innovation Committee of the Federal Joint Committee (Gemeinsamer Bundesausschuss, GBA) 01VSF21029
6 · The paper itself

Abstract

introductionAlcohol use and treatment for alcohol use disorder (AUD) changed during the pandemic. Alcohol consumption increased among high-risk groups, while treatment utilisation declined, raising concerns about an expanding treatment gap. This study analyses inpatient and outpatient AUD treatment trends during the pandemic.

methodsWe analysed electronic health records from 5671 patients residing in Hamburg, Germany, who utilised at least one alcohol-related treatment between January 2016 and December 2021. Data from two statutory health insurance providers and two pension funds provided weekly numbers of patients receiving AUD treatment, including outpatient (psychiatric consultations, psychotherapy, pharmacotherapy), inpatient standard and intensive treatment, and outpatient and inpatient rehabilitation programs. Using a segmented regression approach, we examined changes over time for: (i) any treatment; (ii) outpatient treatment; and (iii) inpatient treatment across five periods of the pandemic: pre-pandemic, first lockdown, between lockdowns, second lockdown and post-second lockdown.

resultsDuring the first lockdown in spring 2020, AUD treatment utilisation declined by 27% before briefly returning to near pre-pandemic levels. A gradual decline was observed in later pandemic periods, even after containment measures were lifted. The decline was more pronounced in inpatient settings than in outpatient settings, at -45% and -15%, respectively, during the first lockdown. DISCUSSION AND

conclusionsThe utilisation of AUD treatment services dropped substantially during the pandemic, particularly in inpatient settings. This reduction may have contributed to the rise in alcohol-related deaths during this period. This study is the first to assess long-term inpatient and outpatient treatment trends across multiple pandemic phases.

Indexed as

AlcoholismCOVID-19PandemicsPatient Acceptance of Health CareAdultAmbulatory CareFemaleGermanyHumansInterrupted Time Series AnalysisMaleMiddle AgedSARS-CoV-2addictiondisruptionhealthcareinterventionmedicationwithdrawal

Identifiers

PMID41591147
PMCPMC12839788

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.