Evidence map›Paper›PMID 41590938›Full record

ArticleJournal of imaging2026

Non-Invasive Detection of Prostate Cancer with Novel Time-Dependent Diffusion MRI and AI-Enhanced Quantitative Radiological Interpretation: PROS-TD-AI.

Baltasar Ramos, Cristian Garrido, Paulette Narváez, Santiago Gelerstein Claro, Haotian Li, Rafael Salvador, Constanza Vásquez-Venegas, Iván Gallegos, Víctor Castañeda, Cristian Acevedo and 2 more

Abstract read
In one paragraph

Article in Journal of imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Baltasar RamosRadiology Department, Clinical Hospital of the University of Chile, University of Chile, Independencia 8380453, Chile.ORCID 0009-0001-6750-1518
Cristian GarridoRadiology Department, Clinical Hospital of the University of Chile, University of Chile, Independencia 8380453, Chile.ORCID 0009-0005-4321-9699
Paulette NarváezUrology Department, Clínica Dávila, Santiago 8431657, Chile.ORCID 0009-0004-6901-4432
Santiago Gelerstein ClaroSchool of Medicine, Faculty of Medicine, University of Chile, Santiago 8380453, Chile.ORCID 0009-0005-6122-1688
Haotian LiKey Laboratory for Biomedical Engineering of the Ministry of Education, College of Biomedical Engineering & Instrument Science, Zhejiang University, Yuquan Campus, 38 Zheda Road, Hangzhou 310027, China.
Rafael SalvadorRadiology Department, Hospital Clinic, Universitat de Barcelona, 170, 08036 Barcelona, Spain.ORCID 0000-0002-8369-6773
Constanza Vásquez-VenegasLaboratory for Scientific Image Analysis SCIAN-Lab, Integrative Biology Program, Institute of Biomedical Sciences ICBM, Faculty of Medicine, University of Chile, Santiago 8380453, Chile.ORCID 0000-0003-0052-7649
Iván GallegosPathology Department, Clinical Hospital of the University of Chile, University of Chile, Independencia 8380453, Chile.ORCID 0000-0002-4692-5194
Víctor CastañedaMedical Technology Department, Faculty of Medicine, University of Chile, Santiago 8380453, Chile.ORCID 0000-0003-0554-0324
Cristian AcevedoUrology Department, Clinical Hospital of the University of Chile, University of Chile, Independencia 8380453, Chile.
Gonzalo CárdenasRadiology Department, Clinical Hospital of the University of Chile, University of Chile, Independencia 8380453, Chile.ORCID 0000-0002-5531-2533
Camilo G SotomayorRadiology Department, Clinical Hospital of the University of Chile, University of Chile, Independencia 8380453, Chile.ORCID 0000-0001-6835-6386

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) is the most common malignancy in men worldwide. Multiparametric MRI (mpMRI) improves the detection of clinically significant PCa (csPCa); however, it remains limited by false-positive findings and inter-observer variability. Time-dependent diffusion (TDD) MRI provides microstructural information that may enhance csPCa characterization beyond standard mpMRI. This prospective observational diagnostic accuracy study protocol describes the evaluation of PROS-TD-AI, an in-house developed AI workflow integrating TDD-derived metrics for zone-aware csPCa risk prediction. PROS-TD-AI will be compared with PI-RADS v2.1 in routine clinical imaging using MRI-targeted prostate biopsy as the reference standard.

Indexed as

artificial intelligenceclinically significant prostate cancerdeep learningGleason scoremagnetic resonance imagingPI-RADS v2.1prostate biopsy

Identifiers

PMID41590938
PMCPMC12843277

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.