Evidence map›Paper›PMID 41590866›Full record

ArticleJournal of cardiovascular development and disease2026

Atrial Fibrillation Recurrence After Catheter Ablation Is Associated with TAG72 Protein.

Karapet V Davtyan, Aishat A Abdullaeva, Nadezhda G Gumanova, Natalya L Bogdanova, Hacob A Brutyan, Elena N Kalemberg, Ekaterina V Bazaeva, Maria S Kharlap, Svetlana E Serdyuk, Oksana M Drapkina

Registry-linked trialAbstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05170607 (Investigation of Specific Biomarkers in Patients With Atrial Fibrillation Who Undergo Interventional Treatment), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05170607 active not recruitingnot on this map

Investigation of Specific Biomarkers in Patients With Atrial Fibrillation Who Undergo Interventional Treatment

TypeobservationalSponsorNational Medical Research Center for Therapy and Preventive MedicineRan2021 to 2028Enrolled120ConditionsAtrial FibrillationArmsProteomic analysis by antibody microarrays
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Karapet V DavtyanNational Medical Research Center for Therapy and Preventive Medicine, Ministry of Health of Russia, 101000 Moscow, Russia.ORCID 0000-0003-3788-3997
Aishat A AbdullaevaNational Medical Research Center for Therapy and Preventive Medicine, Ministry of Health of Russia, 101000 Moscow, Russia.ORCID 0000-0002-3483-3380
Nadezhda G GumanovaNational Medical Research Center for Therapy and Preventive Medicine, Ministry of Health of Russia, 101000 Moscow, Russia.ORCID 0000-0002-6108-3538
Natalya L BogdanovaNational Medical Research Center for Therapy and Preventive Medicine, Ministry of Health of Russia, 101000 Moscow, Russia.ORCID 0000-0002-3124-5655
Hacob A BrutyanNational Medical Research Center for Therapy and Preventive Medicine, Ministry of Health of Russia, 101000 Moscow, Russia.ORCID 0000-0003-4408-3592
Elena N KalembergNational Medical Research Center for Therapy and Preventive Medicine, Ministry of Health of Russia, 101000 Moscow, Russia.ORCID 0000-0001-7199-0353
Ekaterina V BazaevaNational Medical Research Center for Therapy and Preventive Medicine, Ministry of Health of Russia, 101000 Moscow, Russia.ORCID 0000-0002-5405-5459
Maria S KharlapNational Medical Research Center for Therapy and Preventive Medicine, Ministry of Health of Russia, 101000 Moscow, Russia.ORCID 0000-0002-6855-4857
Svetlana E SerdyukNational Medical Research Center for Therapy and Preventive Medicine, Ministry of Health of Russia, 101000 Moscow, Russia.ORCID 0000-0003-4479-6963
Oksana M DrapkinaNational Medical Research Center for Therapy and Preventive Medicine, Ministry of Health of Russia, 101000 Moscow, Russia.ORCID 0000-0003-0323-2635

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the efficacy of catheter ablation in preventing recurrences of atrial fibrillation (AF), the reasons for its lack of success in some patients remain unknown. The aim of this study was to try to identify a new predictor of AF recurrence following catheter-based treatment. This prospective study enrolled a cohort of patients with AF. Based on the results of a one-year follow-up, patients were divided into two groups: Group 1 ("vein-dependent" AF)-patients who achieved a successful outcome after 1-2 catheter ablation procedures-and Group 2 ("non-vein-dependent" AF)-patients with confirmed complete pulmonary vein isolation (PVI) or with an identified "non-vein-dependent" AF substrate. Blood samples were collected prior to the procedure and biobanked. Initial proteomic profiling of the serum using protein microarrays identified several candidate proteins, whose elevated levels were subsequently confirmed by an enzyme-linked immunosorbent assay (ELISA). This article presents data on one such protein-TAG72. A comparison of TAG72 levels (%OD normalized units) between Group 1 ("vein-dependent" AF) and Group 2 ("non-vein-dependent" AF) revealed a statistically significant increase in the latter group (128.9 [98.2; 284.4] vs. 84.3 [73.8; 92.1],

Indexed as

atrial fibrillationatrial fibrillation recurrencebiomarkercatheter ablationpulmonary veins isolationTAG72

Identifiers

PMID41590866
PMCPMC12841881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.