Evidence map›Paper›PMID 41590843›Full record

ArticleJournal of cardiovascular development and disease2025

Comparison of Diastolic Function Parameters After Alcohol Septal Ablation and Mavacamten Therapy in Obstructive Hypertrophic Cardiomyopathy.

Danish Saleh, Ellis Y Kim, Kifah Hussain, Ashraf Samhan, Meilynn Shi, Zhiying Meng, Elizabeth Schormann, Parmeen Bindra, Baljash Cheema, Dominic E Fullenkamp and 6 more

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Danish SalehDepartment of Medicine, Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Ellis Y KimDepartment of Medicine, Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Kifah HussainDepartment of Medicine, Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Ashraf SamhanDepartment of Medicine, Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Meilynn ShiDepartment of Medicine, Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Zhiying MengBluhm Cardiovascular Institute, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Elizabeth SchormannBluhm Cardiovascular Institute, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0000-0003-1089-8670
Parmeen BindraBluhm Cardiovascular Institute, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Baljash CheemaDepartment of Medicine, Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Dominic E FullenkampDepartment of Medicine, Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0001-7627-7119
Abigail S BaldridgeBluhm Cardiovascular Institute, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0000-0002-1573-0554
Jyothy J PuthumanaDepartment of Medicine, Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Vera H RigolinDepartment of Medicine, Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Paul C CremerDepartment of Medicine, Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
James D FlahertyDepartment of Medicine, Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Lubna ChoudhuryDepartment of Medicine, Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac myosin inhibitors have been shown to improve diastolic function in patients with obstructive hypertrophic cardiomyopathy (HCM). Comparative studies to evaluate the diastolic effects of mavacamten versus alcohol septal ablation (ASA) have yet to be examined. In this single-center retrospective analysis, we compared echocardiographic parameters of diastolic function in adult patients with obstructive HCM treated with mavacamten (

Indexed as

alcohol septal ablationdiastolic functionechocardiographyhypertrophic cardiomyopathymavacamten

Identifiers

PMID41590843
PMCPMC12842295

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.