Evidence map›Paper›PMID 41590833›Full record

ReviewJournal of cardiovascular development and disease2025

Fast-Track Extubation After Cardiac Surgery: A Narrative Review.

Alexa Christophides, Stephen DiMaria, Sophia Ann Jacob, Andrew Feit, Jonathan Oster, Sergio Bergese

Abstract readReview
In one paragraph

Review in Journal of cardiovascular development and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexa ChristophidesOffice of the Vice President of Medical Affairs, Northwell Mather Hospital, Port Jefferson, NY 11777, USA.ORCID 0000-0001-8864-0763
Stephen DiMariaDepartment of Anesthesiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Sophia Ann JacobDepartment of Anesthesiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.ORCID 0000-0001-6733-0184
Andrew FeitDepartment of Anesthesiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Jonathan OsterDepartment of Anesthesiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Sergio BergeseDepartment of Anesthesiology, Stony Brook University Hospital, Stony Brook, NY 11794, USA.ORCID 0000-0001-5641-5908

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fast-track extubation has emerged as a vital component of Enhanced Recovery After Surgery pathways, designed to optimize recovery and resource utilization after cardiac surgery, contrasting with traditional prolonged ventilation. This review explores the evidence supporting fast-track extubation, detailing patient selection criteria based on preoperative risk factors and functional status and outlining perioperative management strategies. It synthesizes findings from various studies, including randomized controlled trials, retrospective studies, and meta-analyses, focusing on intraoperative techniques such as low-dose opioids, neuromuscular blockade reversal, controlled cardiopulmonary bypass duration, judicious inotrope use, and minimal transfusion, alongside structured postoperative protocols emphasizing early sedative weaning and spontaneous breathing trials. Results demonstrate that fast-track extubation decreases intensive care unit stay, reduces costs and ventilator-associated complications, with a safety comparable to conventional care. Prolonged cardiopulmonary bypass time, dependency on inotropes, and intraoperative blood transfusions are identified as critical predictors of fast-track extubation failure. In conclusion, the successful implementation of fast-track extubation protocols requires a collaborative, multidisciplinary approach, proving essential for improving patient outcomes, minimizing complications such as postoperative delirium, and enhancing hospital efficiency in cardiac surgery. Further research should aim to refine patient selection and standardize protocols across healthcare systems.

Indexed as

anesthesia managementearly extubationenhanced recovery after surgeryhemodynamic stabilityintensive care unit length of staymultidisciplinary protocolpatient selectionpostoperative recoveryreintubationresource utilization

Identifiers

PMID41590833
PMCPMC12841624

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.