Evidence map›Paper›PMID 41590783›Full record

ArticleJournal of functional biomaterials2025

Multilayer Ti-Cu Oxide Coatings on Ti6Al4V: Balancing Antibacterial Activity, Mechanical Strength, Corrosion Resistance, and Cytocompatibility.

Stefan Valkov, Maria P Nikolova, Tanya V Dimitrova, Maria Elena Stancheva, Dimitar Dechev, Nikolay Ivanov, Yordan Handzhiyski, Andreana Andreeva, Maria Ormanova, Angel Anchev and 1 more

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Stefan ValkovInstitute of Electronics, Bulgarian Academy of Sciences, 72 Tzarigradsko Chaussee Blvd., 1784 Sofia, Bulgaria.ORCID 0000-0003-0416-0549
Maria P NikolovaDepartment of Material Science and Technology, University of Ruse "Angel Kanchev", 8 Studentska Str., 7017 Ruse, Bulgaria.ORCID 0000-0002-0597-7799
Tanya V DimitrovaRoumen Tsanev Institute of Molecular Biology, Bulgarian Academy of Sciences, Acad. Georgi Bonchev Str., Bl. 21, 1113 Sofia, Bulgaria.
Maria Elena StanchevaRoumen Tsanev Institute of Molecular Biology, Bulgarian Academy of Sciences, Acad. Georgi Bonchev Str., Bl. 21, 1113 Sofia, Bulgaria.
Dimitar DechevInstitute of Electronics, Bulgarian Academy of Sciences, 72 Tzarigradsko Chaussee Blvd., 1784 Sofia, Bulgaria.
Nikolay IvanovInstitute of Electronics, Bulgarian Academy of Sciences, 72 Tzarigradsko Chaussee Blvd., 1784 Sofia, Bulgaria.
Yordan HandzhiyskiRoumen Tsanev Institute of Molecular Biology, Bulgarian Academy of Sciences, Acad. Georgi Bonchev Str., Bl. 21, 1113 Sofia, Bulgaria.ORCID 0000-0002-8248-0524
Andreana AndreevaFaculty of Physics, Sofia University "St. Kliment Ohridski", 5 James Bourchier Blvd, 1164 Sofia, Bulgaria.ORCID 0000-0002-7550-6546
Maria OrmanovaInstitute of Electronics, Bulgarian Academy of Sciences, 72 Tzarigradsko Chaussee Blvd., 1784 Sofia, Bulgaria.
Angel AnchevDepartment of Material Science and Mechanics of Materials, Technical University of Gabrovo, 4 H. Dimitar Str., 5300 Gabrovo, Bulgaria.ORCID 0000-0003-4012-7236
Margarita D ApostolovaRoumen Tsanev Institute of Molecular Biology, Bulgarian Academy of Sciences, Acad. Georgi Bonchev Str., Bl. 21, 1113 Sofia, Bulgaria.ORCID 0000-0001-7188-506X

Funding

Bulgarian National Science Fund KП-06-H67-5 (2022)
6 · The paper itself

Abstract

Titanium alloys are widely used for biomedical implants, but their performance is limited by wear, corrosion, and susceptibility to bacterial colonisation. To overcome these drawbacks, multilayer Ti-Cu oxide coatings were deposited on Ti6Al4V substrates using direct current magnetron sputtering. Two multilayer architectures (6 × 2 and 12 × 2 TiO

Indexed as

antibacterial propertiesCuO–TiO2 thin filmscytocompatibilityelectrochemical behaviourmagnetron sputteringmetallothioneinmultilayer coatingsPVD coatingssurface engineeringTi6Al4V

Identifiers

PMID41590783
PMCPMC12842340

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.