Evidence map›Paper›PMID 41590773›Full record

ArticleJournal of functional biomaterials2025

Modification of Physico-Chemical and Biological Characteristics of Polymethylmethacrylate with Amorphous Carbon Nanoparticles for Counteracting Healthcare-Associated Infections.

Sergey V Gudkov, Dmitriy A Serov, Ruslan M Sarimov, Vasiliy S Novikov, Maksim Moskovskiy, Maksim B Rebezov, Mikhail V Dubinin, Konstantin V Sergienko, Mikhail A Sevostyanov, Fatikh M Yanbaev and 2 more

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review of Antimicrobial Properties of Carbon Nanomaterials.International journal of molecular sciences · 2026
    Review
  2. A Composite Based onPolymers · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sergey V GudkovProkhorov General Physics Institute of the Russian Academy of Sciences, Vavilov St. 38, 119991 Moscow, Russia.ORCID 0000-0002-8814-6906
Dmitriy A SerovProkhorov General Physics Institute of the Russian Academy of Sciences, Vavilov St. 38, 119991 Moscow, Russia.ORCID 0000-0002-6049-5602
Ruslan M SarimovProkhorov General Physics Institute of the Russian Academy of Sciences, Vavilov St. 38, 119991 Moscow, Russia.ORCID 0000-0002-2751-1615
Vasiliy S NovikovProkhorov General Physics Institute of the Russian Academy of Sciences, Vavilov St. 38, 119991 Moscow, Russia.ORCID 0000-0002-3304-1568
Maksim MoskovskiyFederal Scientific Agroengineering Center VIM, 109428 Moscow, Russia.ORCID 0000-0001-5727-8706
Maksim B RebezovDepartment of Scientific Research, Gorbatov Research Center for Food Systems, Talalikhin St. 26, 109316 Moscow, Russia.ORCID 0000-0003-0857-5143
Mikhail V DubininProkhorov General Physics Institute of the Russian Academy of Sciences, Vavilov St. 38, 119991 Moscow, Russia.ORCID 0000-0002-7453-3390
Konstantin V SergienkoBaikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences (IMET RAS), Leninsky Prospekt 49, 119334 Moscow, Russia.ORCID 0000-0003-4018-4599
Mikhail A SevostyanovBaikov Institute of Metallurgy and Materials Science, Russian Academy of Sciences (IMET RAS), Leninsky Prospekt 49, 119334 Moscow, Russia.
Fatikh M YanbaevFederal Research Center "Kazan Scientific Center of the Russian Academy of Sciences", Lobachevskogo St. 2/31, 420088 Kazan, Russia.
Maxim E AstashevProkhorov General Physics Institute of the Russian Academy of Sciences, Vavilov St. 38, 119991 Moscow, Russia.
Maria V VedunovaProkhorov General Physics Institute of the Russian Academy of Sciences, Vavilov St. 38, 119991 Moscow, Russia.ORCID 0000-0001-9759-6477

Funding

Ministry of Science and Higher Education of the Russian Federation 075-15-2024-646
6 · The paper itself

Abstract

Composite materials based on polymethylmethacrylate (PMMA) and carbon nanoparticles are used in aviation, construction, medical and other fields of activity. Carbon nanotubes and carbon nano-dots are mainly used as carbon nanoparticles. Both carbon nanotube and carbon nano-dots are difficult to obtain materials with considerable cost. Amorphous carbon nanoparticles, on the contrary, are easy to obtain and have a low cost. The purpose of this work is to study the physico-chemical and biological characteristics of polymethylmethacrylate modified with amorphous carbon nanoparticles. Laser ablation was used to obtain the nanoparticles. Dynamic light scattering, measurement of the electrokinetic potential, TEM, AFM, and Raman microscopy are used to characterize nanoparticles. FTIR, MIM, AFM, UV-visual diagnostics, ROS tests, and biopolymer regeneration tests were used to analyze the combined sensors. The bacteriostatic effect was evaluated using turbodimetry, and the antibacterial effect was evaluated using precision cytofluorometry. Mammalian cells were examined using fluorescence microscopy. Carbon nanoparticles (CNPs) have been obtained and characterized. A protocol has been developed for the introduction of CNPs into photolithographic resin. Printed samples of complex geometry. It is shown that the printed samples are amenable to polishing, have pro-oxidant properties, and are able to prevent damage to biopolymers. Printed samples inhibit the development of bacteria and cause loss of viability. At the same time, the printed samples do not affect the development of mammalian cells. The obtained resins based on PMMA with CNPs can potentially serve as the basis for the creation of non-toxic materials in biomedicine and pharmacology.

Indexed as

amorphous carbon nanoparticlesantibacterial and non-toxic to mammalian cellsMSLApolymer compositepolymethyl methacrylate-like resin

Identifiers

PMID41590773
PMCPMC12841775

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.