Evidence map›Paper›PMID 41590729›Full record

ArticleMarine drugs2026

Integrating Computational and Experimental Approaches for the Discovery of Multifunctional Peptides from the Marine Gastropod

Ernesto M Martell-Huguet, Thalia Moran-Avila, José E Villuendas, Armando Rodriguez, Ann-Kathrin Kissmann, Ludger Ständker, Sebastian Wiese, Anselmo J Otero-Gonzalez, Frank Rosenau

Abstract read
In one paragraph

Article in Marine drugs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ernesto M Martell-HuguetInstitute of Pharmaceutical Biotechnology, Ulm University, 89081 Ulm, Germany.ORCID 0000-0001-6494-800X
Thalia Moran-AvilaCenter for Protein Studies, Faculty of Biology, University of Havana, 25 and I, La Habana 10400, Cuba.ORCID 0009-0002-5776-8187
José E VilluendasCenter for Protein Studies, Faculty of Biology, University of Havana, 25 and I, La Habana 10400, Cuba.ORCID 0009-0008-4784-2535
Armando RodriguezULMTec Core Facility of Mass Spectrometry and Proteomics, Faculty of Medicine, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.ORCID 0000-0001-5921-3770
Ann-Kathrin KissmannInstitute of Pharmaceutical Biotechnology, Ulm University, 89081 Ulm, Germany.ORCID 0000-0002-7164-0166
Ludger StändkerULMTec Core Facility for Functional Peptidomics, Ulm Peptide Pharmaceuticals (U-PEP), Faculty of Medicine, Ulm University, 89081 Ulm, Germany.ORCID 0000-0002-8436-4260
Sebastian WieseULMTec Core Facility of Mass Spectrometry and Proteomics, Faculty of Medicine, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.ORCID 0000-0001-5697-2608
Anselmo J Otero-GonzalezCenter for Protein Studies, Faculty of Biology, University of Havana, 25 and I, La Habana 10400, Cuba.ORCID 0000-0002-1719-0117
Frank RosenauInstitute of Pharmaceutical Biotechnology, Ulm University, 89081 Ulm, Germany.ORCID 0000-0002-9297-6419

Funding

Bundesministerium für Forschung, Technologie und Raumfahrt DLR CUB 17WTZ-014/01DN18009Deutsche Forschungsgemeinschaft (DFG) 465229237Deutsche Forschungsgemeinschaft (DFG) CRC1279German Academic Exchange Service 57592717-Glacier
6 · The paper itself

Abstract

Marine invertebrates are a prime source of biologically active peptides due to their role in humoral immunity. These peptides typically exhibit broad-spectrum functions, including antibacterial, antifungal, anticancer, and immunomodulatory activities. In this report, we describe the identification and biological characterization of five novel bioactive peptides from the marine mollusk

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsAntimicrobial PeptidesAntineoplastic AgentsGastropodaPeptidesAnimalsCell Line, TumorComputational BiologyHumansMicrobial Sensitivity TestsPseudomonas aeruginosaAnti-Bacterial AgentsAnti-Infective AgentsAntimicrobial PeptidesAntineoplastic AgentsPeptidesanticancer activityantimicrobial peptidesin silico predictionsmarine mollusks

Identifiers

PMID41590729
PMCPMC12843047

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.