Evidence map›Paper›PMID 41590543›Full record

ArticleJournal of personalized medicine2026

Functional, Cohort-Level Assessment of CFTR Modulator Responses Using Biobanked Nasal Epithelial Cells from Individuals with Cystic Fibrosis.

Bente L Aalbers, Gimano D Amatngalim, Ellen M Aarts, Lisa W Rodenburg, Loes A den Hertog-Oosterhoff, Harry G M Heijerman, Jeffrey M Beekman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of personalized medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bente L AalbersDepartment of Pulmonology, University Medical Center Utrecht, 3584 EA Utrecht, The Netherlands.
Gimano D AmatngalimLab of Cellular Disease Models, Department of Pediatrics, Regenerative Medicine Center Utrecht, University Medical Center Utrecht, 3584 CT Utrecht, The Netherlands.ORCID 0000-0003-3442-1754
Ellen M AartsLab of Cellular Disease Models, Department of Pediatrics, Regenerative Medicine Center Utrecht, University Medical Center Utrecht, 3584 CT Utrecht, The Netherlands.ORCID 0000-0001-8714-061X
Lisa W RodenburgLab of Cellular Disease Models, Department of Pediatrics, Regenerative Medicine Center Utrecht, University Medical Center Utrecht, 3584 CT Utrecht, The Netherlands.ORCID 0000-0002-8113-4304
Loes A den Hertog-OosterhoffLab of Cellular Disease Models, Department of Pediatrics, Regenerative Medicine Center Utrecht, University Medical Center Utrecht, 3584 CT Utrecht, The Netherlands.
Harry G M HeijermanDepartment of Pulmonology, University Medical Center Utrecht, 3584 EA Utrecht, The Netherlands.
Jeffrey M BeekmanLab of Cellular Disease Models, Department of Pediatrics, Regenerative Medicine Center Utrecht, University Medical Center Utrecht, 3584 CT Utrecht, The Netherlands.

Funding

Dutch Cystic Fibrosis Foundation HIT-CF grantthe Netherlands Organization for Health Research and Development (ZonMw); Health Holland grant no 40-41200-98-9296
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

air-liquid interface (ALI) culturesbiobankingcystic fibrosisnasal epithelial cellstheratypingUssing chamber

Identifiers

PMID41590543
PMCPMC12842762

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.