Evidence map›Paper›PMID 41590440›Full record

ArticleJournal of fungi (Basel, Switzerland)2025

Genome Mining and Heterologous Reconstitution of a PKS-NRPS Gene Cluster from

Quan Dai, Yiqiao Li, Shuzhe Lv, Shuang Zhao, Liyuan Han, Jiaxin Xu, Hui Shuai, Youming Zhang, Fu Yan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Quan DaiState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Yiqiao LiState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Shuzhe LvState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Shuang ZhaoState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Liyuan HanState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Jiaxin XuState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Hui ShuaiState Key Laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine, Lunan Pharmaceutical Group Co., Ltd., Linyi 276005, China.
Youming ZhangState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Fu YanState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.ORCID 0000-0002-4731-3376

Funding

The Major Basic Research Project of the Natural Science Foundation of Shandong Province ZR2023ZD29
6 · The paper itself

Abstract

Heterologous expression of silent biosynthetic gene clusters represents a key strategy for the discovery of structurally novel natural products. In this study, we obtained ten new tetronate natural products, designated as talactones A-J (

Indexed as

antibacterial activityAspergillus flavipes LY1-5heterologous expressiontalactones A–Jtetronate

Identifiers

PMID41590440
PMCPMC12843353

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.