ReviewJournal of fungi (Basel, Switzerland)2025
From the Ground to the Clinic: The Evolution and Adaptation of Fungi.
Review in Journal of fungi (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Fungal DNA damage repair: from model to driver of virulence and AMR.Bioscience reports · 2026Review
- Amplicon Sequencing Reveals Microbial Community Structure and Its Relationships with Environmental Factors inMicroorganisms · 2026Article
- Epigenetic Inhibitor 5-Azacytidine Triggers DIM-2/DIM-5-Dependent Mutagenesis in H3K9me3-Enriched Regions ofJournal of fungi (Basel, Switzerland) · 2026Article
- Cassette-Based Automated Production of 2-Deoxy-2-[Molecules (Basel, Switzerland) · 2026Article
- Editorial: Evolutionary adaptation in human-infecting fungi: ecological traits and pathogenicity.Frontiers in cellular and infection microbiology · 2026Article
- The roles ofFrontiers in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Fungi constitute a diverse kingdom of eukaryotic organisms with remarkable adaptability, ranging from saprophytic decomposers to lethal human pathogens. This review synthesizes current insights into fungal adaptations that underline pathogenesis, focusing on enzymatic strategies including hydrolytic enzymes, metabolic and physiological plasticity such as thermotolerance and nutrient flexibility, and evasion of host immunity via mechanisms like melanin production and biofilm formation. We detail fungal survival tactics including spore formation and genomic and epigenetic plasticity, which contribute to resilience and evolution under environmental and host-imposed stresses. The escalating emergence of antifungal resistance and the global impact of environmental changes underscore urgent clinical challenges. Advances in diagnostics, novel therapeutics incorporating AI-assisted drug discovery, and integrated One Health approaches are poised to combat this growing threat. This comprehensive overview aims to guide future research and inform clinical management of fungal infections in an era of dynamic microbial evolution and environmental upheaval.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.