Evidence map›Paper›PMID 41590384›Full record

ReviewCurrent oncology (Toronto, Ont.)2026

Anal Squamous Cell Carcinoma with Bilateral Renal Metastases: A Rare Presentation with Literature Review.

Khujasta Gul, Saivaishnavi Kamatham, Guido Chiriboga, Ahmed Abdelhakeem, Aziza Nassar, Conor O'Donnell, Umair Majeed

Abstract readCase ReportsReview
In one paragraph

Review in Current oncology (Toronto, Ont.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Khujasta GulDepartment of Hematology/Oncology, Mayo Clinic Florida, Jacksonville, FL 32224, USA.ORCID 0009-0004-2094-8939
Saivaishnavi KamathamDepartment of Hematology/Oncology, Mayo Clinic Florida, Jacksonville, FL 32224, USA.
Guido ChiribogaMayo Clinic Alix School of Medicine, Jacksonville, FL 32224, USA.ORCID 0009-0008-0858-0560
Ahmed AbdelhakeemDepartment of Hematology/Oncology, Mayo Clinic Florida, Jacksonville, FL 32224, USA.
Aziza NassarDepartment of Pathology, Mayo Clinic Florida, Jacksonville, FL 32224, USA.ORCID 0000-0002-6678-9329
Conor O'DonnellDepartment of Hematology/Oncology, Mayo Clinic Florida, Jacksonville, FL 32224, USA.ORCID 0009-0009-6291-846X
Umair MajeedDepartment of Hematology/Oncology, Mayo Clinic Florida, Jacksonville, FL 32224, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anal squamous cell carcinoma (ASCC) is a rare malignancy of the lower gastrointestinal tract, with distant metastases typically involving the liver and lungs. Metastasis to the kidneys is uncommon, and only one prior case has been reported in the literature. Herein, we report a rare presentation of a patient with biopsy-confirmed metastatic ASCC presenting as bilateral renal lesions. We then provide a review of the literature for rare metastatic presentations of ASCC, highlighting all the cases described in the literature. Clinicians should maintain a high index of suspicion for unusual metastatic sites, perform targeted imaging and biopsy when indicated, and consider systemic therapies to optimize outcomes in rare metastatic presentations.

Indexed as

Anus NeoplasmsCarcinoma, Squamous CellKidney NeoplasmsHumansMaleMiddle Agedanal squamous cell carcinomabilateral renal metastaseschemoradiotherapyimmunotherapyrare metastasis

Identifiers

PMID41590384
PMCPMC12839839

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.