Evidence map›Paper›PMID 41590367›Full record

ArticleCurrent oncology (Toronto, Ont.)2026

Unique Clinical Features of Imaging-Stage I Peripheral Lung Squamous Cell Carcinoma: A Retrospective Study.

Chengzhang Xiong, Wenjing Zhang, Qing Wang, Hao Yin, Jibin Chen, Wenjun Jiang, Xu Han

Abstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chengzhang XiongDepartment of Thoracic Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang 110032, China.ORCID 0009-0005-1979-2110
Wenjing ZhangDepartment of Thoracic Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang 110032, China.
Qing WangDepartment of Thoracic Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang 110032, China.ORCID 0000-0002-2606-4323
Hao YinDepartment of Thoracic Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang 110032, China.
Jibin ChenDepartment of Thoracic Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang 110032, China.
Wenjun JiangDepartment of Thoracic Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang 110032, China.
Xu HanDepartment of Thoracic Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang 110032, China.ORCID 0000-0003-1327-4329

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of peripheral lung squamous cell carcinoma (p-LUSC) has increased in recent years, but the clinical features of early-stage p-LUSC remain unclear. In the present study, we aim to elucidate the general clinical features of p-LUSC by comparing it with peripheral lung adenocarcinoma (p-LUAD). Patients with p-LUSC or p-LUAD who were at an early imaging stage and underwent complete lobectomy with systematic lymph node dissection were included. The clinical characteristics of p-LUSC were elucidated through comparative analysis with p-LUAD, and independent prognostic factors for recurrence-free survival were identified. A total of 103 patients with p-LUSC and 600 patients with p-LUAD were included. Compared with p-LUAD, all p-LUSC cases appeared as solid nodules (SDNs) on imaging, and p-LUSC was associated with the male sex, older age, smoking history, lobulation sign, interstitial pneumonia, and a shorter volume doubling time. In terms of malignant aggressiveness, p-LUSC demonstrated a significantly lower lymph node metastasis rate than SDNs of p-LUAD in the >2.0 to ≤3.0 cm group, while no statistically significant difference was observed between the two groups in the 0-2.0 cm group. As for prognosis, tumor size and lymph node metastasis were found as independent risk factors for tumor recurrence.

Indexed as

Carcinoma, Squamous CellLung NeoplasmsAgedFemaleHumansMaleMiddle AgedNeoplasm StagingPrognosisRetrospective Studiescomputed tomographyperipheral lung squamous cell carcinomaprognostic factorvolume doubling time

Identifiers

PMID41590367
PMCPMC12840133

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.