Improving Prognostic Prediction in Head and Neck Cancer Through a Combined Systemic Immune-Inflammation Index and Prognostic Nutritional Index Score.

Takuya Miura, Hisashi Kessoku, Masato Nagaoka, Yohei Morishita, Toshiki Kobayashi, Hiromi Kojima

Abstract read

In one paragraph

Article in Current oncology (Toronto, Ont.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed, 1 pooled it

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

Prognostic Value of the Haemoglobin-Albumin-Lymphocyte-Platelet Score in Head and Neck Cancer: A Systematic Review and Meta-Analysis.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2026
Pooled it

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Takuya MiuraDepartment of Otorhinolaryngology and Head and Neck Surgery, Jikei University Kashiwa Hospital, Kashiwa 277-8567, Japan.ORCID 0009-0006-6623-2375

Hisashi KessokuDepartment of Otorhinolaryngology and Head and Neck Surgery, Jikei University Kashiwa Hospital, Kashiwa 277-8567, Japan.

Masato NagaokaDepartment of Otorhinolaryngology, Jikei University Hospital, Tokyo 105-0003, Japan.

Yohei MorishitaDepartment of Otorhinolaryngology and Head and Neck Surgery, Jikei University Kashiwa Hospital, Kashiwa 277-8567, Japan.

Toshiki KobayashiDepartment of Otorhinolaryngology and Head and Neck Surgery, Jikei University Kashiwa Hospital, Kashiwa 277-8567, Japan.

Hiromi KojimaDepartment of Otorhinolaryngology, Jikei University Hospital, Tokyo 105-0003, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated whether a composite index combining the systemic immune-inflammation index (SII) and prognostic nutritional index (PNI), the coSII-PNI score, enhances prognostic prediction in head and neck cancer. We retrospectively evaluated 166 patients who underwent curative surgery between 2015 and 2023. Patients were stratified into three groups according to the coSII-PNI score (range, 0-2) derived from preoperative blood data. The optimal cutoff values for SII and PNI were 743 and 49, respectively. A significant correlation was observed between the SII and PNI (r = -0.386,

Indexed as

Head and Neck NeoplasmsInflammationNutrition AssessmentAgedFemaleHumansMaleMiddle AgedNutritional StatusPrognosisRetrospective Studieshead and neck cancerprognostic nutritional indexsystemic immune–inflammation index

Identifiers

PMID41590350

DOI10.3390/curroncol33010030

PMCPMC12839689

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.