ArticleBiosensors2026
Metallic Flexible NiTi Wire Microcrack Transducer for Label-Free Impedimetric Sensing of
Article in Biosensors, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Flexible biosensors offer rapid and low-cost diagnostics but are often limited by the mechanical and electrochemical instability of polymer-based designs in biological media. Here, we introduce a metallic flexible microcrack transducer that exploits the intrinsic deformability of superelastic nickel-titanium (NiTi) for label-free impedimetric detection. Mechanical bending of NiTi wires spontaneously generates martensitic-phase microcracks whose metal-gap-metal geometry forms the active transduction sites, where functional interfacial layers and captured analytes modulate the local dielectric environment and govern the impedance response. Our approach imparts a novel dielectric character to the alloy, enabling its unexplored application in the megahertz (MHz) frequency domain (0.01-10 MHz) where native NiTi is merely conductive. Functionalization with
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