Evidence map›Paper›PMID 41590092›Full record

ArticleGels (Basel, Switzerland)2026

Lysozyme Functionalized Alginate-Chitosan Beads and Films for Different Release Applications.

Beatriz Moutinho, Natalia Pyra, Zuzanna Styrna, Maria Emilia Rosa, Maria H L Ribeiro

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Beatriz MoutinhoResearch Institute of Medicines, Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal.
Natalia PyraResearch Institute of Medicines, Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal.
Zuzanna StyrnaResearch Institute of Medicines, Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal.ORCID 0009-0003-1080-3317
Maria Emilia RosaInstituto de Engenharia Mecânica (IDMEC), Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal.
Maria H L RibeiroResearch Institute of Medicines, Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisboa, Portugal.ORCID 0000-0001-5693-7861

Funding

Fundação Ciencia e Tecnologia UID 04138 - Instituto de Investigação do Medicamento
6 · The paper itself

Abstract

The main goal of this work was to develop nanoparticles of lysozyme (Lys) for biological and biomedical applications. The developed biosystems were based on Lys-loaded calcium alginate 2% and chitosan 1% beads and films with different concentrations of each polymer. Encapsulation efficiency was 100%. The ratio of adsorbed Lys on the films, Lys activity, and the release profile of Lys were measured using water and buffer solution at pH similar to the environment of cancer cells, at a controlled temperature of 37 °C and a constant speed, to assess the efficacy of the encapsulation process. Lys antimicrobial activity was assessed using

Indexed as

alginateanti-inflammatory activityantioxidant activitychitosanhydrogelslysozyme

Identifiers

PMID41590092
PMCPMC12840807

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.