Evidence map›Paper›PMID 41590091›Full record

ArticleGels (Basel, Switzerland)2026

Biomedical Interpenetrated Hydrogels Fabricated via Quaternary Ammonium Chitosan and Dopamine-Conjugated Gelatin Integrated with Genipin and Epigallocatechin Gallate.

Ling Wang, Shuxin Hu, Zheng Wei, Peng Ding, Yaling Deng, Yanting Han, Yanfang Sun, Guohua Jiang, Lei Nie

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ling WangCollege of Life Sciences, Xinyang Normal University (XYNU), Xinyang 464000, China.
Shuxin HuCollege of Life Sciences, Xinyang Normal University (XYNU), Xinyang 464000, China.
Zheng WeiCollege of Life Sciences, Xinyang Normal University (XYNU), Xinyang 464000, China.
Peng DingCollege of Life Sciences, Xinyang Normal University (XYNU), Xinyang 464000, China.
Yaling DengCollege of Intelligent Science and Control Engineering, Jinling Institute of Technology, Nanjing 211169, China.ORCID 0000-0003-0328-0450
Yanting HanCollege of Life Sciences, Xinyang Normal University (XYNU), Xinyang 464000, China.
Yanfang SunCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.
Guohua JiangSchool of Materials Science and Engineering, Zhejiang Sci-Tech University, Hangzhou 310018, China.
Lei NieCollege of Life Sciences, Xinyang Normal University (XYNU), Xinyang 464000, China.ORCID 0000-0002-6175-5883

Funding

National Natural Science Foundation of China 32571576National Natural Science Foundation of China 52405195
6 · The paper itself

Abstract

Multifunctional hydrogels with an interpenetrated network structure have shown great potential for biomedical and tissue-regeneration applications. In this work, the biomedical hydrogel was fabricated with an interpenetrated network based on dopamine grafted gelatin (DA-Gel), and genipin crosslinked quaternary ammonium chitosan (QCS), incorporating epigallocatechin gallate (EGCG). The EDC/NHS and Schiff-base bond connections occurred in the hydrogels, as confirmed by Fourier-transform infrared (FT-IR) analysis. The properties of the fabricated hydrogels, including microstructure, degradation rate, adhesive strength, mechanical strength, and rheological behavior, can be regulated by adjusting the DA-Gel/QCS ratio or by using different crosslinking approaches. In addition, the fabricated hydrogels exhibited self-healing properties and strong adhesion to various materials and organs. Furthermore, the hydrogels performed good antibacterial activity against the typical bacteria,

Indexed as

chitosanEGCGgelatingenipinhydrogels

Identifiers

PMID41590091
PMCPMC12840651

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.