Evidence map›Paper›PMID 41590039›Full record

ArticleGels (Basel, Switzerland)2025

Design and In Vitro Evaluation of Cross-Linked Poly(HEMA)-Pectin Nano-Composites for Targeted Delivery of Potassium Channel Blockers in Cancer Therapy.

Gizem Ozkurnaz Civir, Fatemeh Bahadori, Ozgur Ozay, Gamze Ergin Kızılçay, Seyma Atesoglu, Ebru Haciosmanoglu Aldogan, Burak Celik

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gizem Ozkurnaz CivirDepartment of Biotechnology, Institute of Health Sciences, Bezmialem Vakif University, 34093 Fatih, Istanbul, Türkiye.
Fatemeh BahadoriDepartment of Analytical Chemistry, Faculty of Pharmacy, Istanbul University-Cerrahpasa, Buyukcekmece Campus, 34500 Buyukcekmece, Istanbul, Türkiye.ORCID 0000-0003-4224-9309
Ozgur OzayLaboratory of Biomaterials Research, Department of Bioengineering, Faculty of Engineering, Çanakkale Onsekiz Mart University, 17100 Çanakkale, Türkiye.ORCID 0000-0001-6589-9844
Gamze Ergin KızılçayDepartment of Analytical Chemistry, Faculty of Pharmacy, Istanbul University, Beyazıt, 34116 Fatih, Istanbul, Türkiye.ORCID 0000-0002-1089-7195
Seyma AtesogluDepartment of Biotechnology, Institute of Health Sciences, Bezmialem Vakif University, 34093 Fatih, Istanbul, Türkiye.
Ebru Haciosmanoglu AldoganDepartment of Biophysics, Faculty of Medicine, Bezmialem Vakif University, 34093 Fatih, Istanbul, Türkiye.ORCID 0000-0001-9559-4515
Burak CelikDepartment of Pharmaceutical Biotechnology, Faculty of Pharmacy, Bezmialem Vakif University, 34093 Fatih, Istanbul, Türkiye.ORCID 0000-0003-0469-4532

Funding

Bezmialem University 20210606
6 · The paper itself

Abstract

Potassium (K

Indexed as

A549 lung cancer cellsazimilidedofetilideEPR effectHEMA-pectin nanoparticlespotassium channel blockerstargeted cancer therapy

Identifiers

PMID41590039
PMCPMC12841014

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.